Mañana, JUEVES, 24 DE ABRIL, el sistema se apagará debido a tareas habituales de mantenimiento a partir de las 9 de la mañana. Lamentamos las molestias.
Durable complete remission of a brainstem glioma treated with a combination of bevacizumab and cetuximab
Entity
UAM. Departamento de MedicinaPublisher
Karger AGDate
2012-09-01Citation
10.1159/000341852
Case Reports in Oncology 5 (2012): 676-681
ISSN
1662–6575DOI
10.1159/000341852Editor's Version
http://dx.doi.org/10.1159/000341852Subjects
Bevacizumab; Cetuximab; Durable remission; Glioma; MedicinaRights
© 2012 S. Karger AG, BaselAbstract
Treatment of a relapsed glioma is a clinical challenge nowadays. New active treatments are required to treat these difficult diseases. Here we present a durable complete remission of a relapsed glioblastoma that has achieved a complete radiologic response with the combination of cetuximab and bevacizumab, in a third-line setting, that has offered a progression-free survival of 20 months. We consider here both potential mechanisms for the explanation of this result. First, the potential target of the cancer stem cells (CSCs) with these two antibodies, and second, the potential recruitment of the immune system to directly pursue the CSCs
Files in this item
Google Scholar:Gasent Blesa, Joan Manel
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Blasco Mollá, Sara
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Fonfría Esparcia, María
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Sempere Ortells, JoséMiguel Miguel
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Peris Godoy, Miguel
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Munilla Das, Adrián
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Mancheño Magán, Balbino
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Provencio Pulla, Mariano
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Sánchez, José Luis Aparicio
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Bautista Laforga Canales, Juan
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Alberola Candel, Vicente
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