Preparation of hollow magnetite microspheres and their applications as drugs carriers
Entity
UAM. Departamento de Física AplicadaPublisher
Springer New YorkDate
2012-04-10Citation
10.1186/1556-276X-7-210
Nanoscale Research Letters 7(2012): 210
ISSN
1931-7573 (print); 1556-276X (online)DOI
10.1186/1556-276X-7-210Funded by
The authors gratefully recognize the financial support provided by the Department of Energy through the Massey Chair project at University of Turabo and from the National Science Foundation through the contract CHE-0959334. Financial support from MICINN (Spain) through the grant MAT2010-19804 is also acknowledged. The “Servicio Interdepartamental de Investigación (SIdI)” from Universidad Autónoma de Madrid and “Centro de Microscopía Luis Bru” from Universidad Complutense de Madrid are acknowledged for the use of the FE-SEM and HRTEM facilities. OPP also acknowledges the support from The National Science Foundation under Grant No. HRD 0833112 (CREST program)Editor's Version
http://dx.doi.org/10.1186/1556-276X-7-210Subjects
Fe304; Drug carrier; Rhodamine-B; Methotrexate; FísicaRights
© 2012 Marquez et al.Abstract
Hollow magnetite microspheres have been synthesized by a simple process through a templatefree hydrothermal approach. Hollow microspheres were surface modified by coating with a silica nanolayer. Pristine and modified hollow microparticles were characterized by field-emission electron microscopy, transmission electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy, FT-IR and Raman spectroscopy, and VSM magnetometry. The potential application of the modified hollow magnetite microspheres as a drug carrier was evaluated by using Rhodamine B and methotrexate as model drugs. The loading and release kinetics of both molecules showed a clear pH and temperature dependent profile
Files in this item
Google Scholar:Márquez, Francisco
-
Herrera, Gloria, M.
-
Campo, Teresa
-
Cotto, María
-
Ducongé, José
-
Sanz Martínez, José María
-
Elizalde, Eduardo
-
Perales, Óscar
-
Morant Zacarés, Carmen
This item appears in the following Collection(s)
Related items
Showing items related by title, author, creator and subject.