dc.contributor.author | Fernandez-Mendoza, Julio | |
dc.contributor.author | Vgontzas, Alexandros N. | |
dc.contributor.author | Bixler, Edward O. | |
dc.contributor.author | Singareddy, Ravi | |
dc.contributor.author | Shaffer, Michele L. | |
dc.contributor.author | Calhoun, Susan L. | |
dc.contributor.author | Karataraki, Maria | |
dc.contributor.author | Vela Bueno, Antonio | |
dc.contributor.author | Liao, Duanping | |
dc.contributor.other | UAM. Departamento de Psiquiatría | es_ES |
dc.date.accessioned | 2015-10-22T14:32:24Z | |
dc.date.available | 2015-10-22T14:32:24Z | |
dc.date.issued | 2012 | |
dc.identifier.citation | Sleep 35.5 (2012): 689-697 | en_US |
dc.identifier.issn | 0161-8105 (print) | en_US |
dc.identifier.issn | 1550-9109 (online) | en_US |
dc.identifier.uri | http://hdl.handle.net/10486/668643 | |
dc.description.abstract | Study Objectives: Approximately 8-10% of the general population suffers from chronic insomnia, whereas another 20-30% of the population has
insomnia symptoms at any given time (i.e., poor sleep). However, few longitudinal studies have examined risk factors of the natural history of poor
sleep, and none have examined the role of polysomnographic (PSG) variables.
Design: Representative longitudinal study.
Setting: Sleep laboratory.
Participants: From a random, general population sample of 1,741 individuals of the adult Penn State Cohort, 1,395 were followed up after 7.5 yr.
Measurements: Full medical evaluation and 1-night PSG at baseline and telephone interview at follow-up.
Results: The rate of incident poor sleep was 18.4%. Physical (e.g., obesity, sleep apnea, and ulcer) and mental (e.g., depression) health conditions
and behavioral factors (e.g., smoking and alcohol consumption) increased the odds of incident poor sleep as compared to normal sleep. The rates
of persistent, remitted, and poor sleepers who developed chronic insomnia were 39%, 44%, and 17%, respectively. Risk factors for persistent poor
sleep were physical health conditions combined with psychologic distress. Shorter objective sleep duration and a family history of sleep problems
were risk factors for poor sleep evolving into chronic insomnia.
Conclusions: Poor sleep appears to be primarily a symptom of physical and mental health conditions, whereas the persistence of poor sleep is
associated with psychologic distress. Importantly, sleep apnea appears to be associated with incident poor sleep but not with chronic insomnia.
Finally, this study suggests that objective short sleep duration in poor sleepers is a biologic marker of genetic predisposition to chronic insomnia | en_US |
dc.description.sponsorship | This research was funded in part by the National Institutes of
Health grants RO1 51931, RO1 40916 (to Dr. Bixler), and RO1
64415 (to Dr. Vgontzas). | en_US |
dc.format.extent | 9 pag. | es_ES |
dc.format.mimetype | application/pdf | en |
dc.language.iso | eng | en |
dc.publisher | American Academy of Sleep Medicine | en_US |
dc.relation.ispartof | Sleep | en_US |
dc.rights | © 2012 Associated Professional Sleep Societies | en_US |
dc.subject.other | Incidence | en_US |
dc.subject.other | Persistence | en_US |
dc.subject.other | Poor sleep | en_US |
dc.subject.other | Chronic insomnia | en_US |
dc.subject.other | Polysomnography | en_US |
dc.title | Clinical and polysomnographic predictors of the Natural History of poor sleep in the general population | en_US |
dc.type | article | en |
dc.subject.eciencia | Medicina | es_ES |
dc.relation.publisherversion | http://dx.doi.org/10.5665/sleep.1832 | es_ES |
dc.identifier.doi | 10.5665/sleep.1832 | es_ES |
dc.identifier.publicationfirstpage | 689 | es_ES |
dc.identifier.publicationissue | 5 | es_ES |
dc.identifier.publicationlastpage | 697 | es_ES |
dc.identifier.publicationvolume | 35 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | en |
dc.rights.accessRights | openAccess | en |
dc.authorUAM | Vela Bueno, Antonio (258967) | |
dc.facultadUAM | Facultad de Medicina | |