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dc.contributor.authorFernandez-Mendoza, Julio
dc.contributor.authorVgontzas, Alexandros N.
dc.contributor.authorBixler, Edward O.
dc.contributor.authorSingareddy, Ravi
dc.contributor.authorShaffer, Michele L.
dc.contributor.authorCalhoun, Susan L.
dc.contributor.authorKarataraki, Maria
dc.contributor.authorVela Bueno, Antonio
dc.contributor.authorLiao, Duanping
dc.contributor.otherUAM. Departamento de Psiquiatríaes_ES
dc.date.accessioned2015-10-22T14:32:24Z
dc.date.available2015-10-22T14:32:24Z
dc.date.issued2012
dc.identifier.citationSleep 35.5 (2012): 689-697en_US
dc.identifier.issn0161-8105 (print)en_US
dc.identifier.issn1550-9109 (online)en_US
dc.identifier.urihttp://hdl.handle.net/10486/668643
dc.description.abstractStudy Objectives: Approximately 8-10% of the general population suffers from chronic insomnia, whereas another 20-30% of the population has insomnia symptoms at any given time (i.e., poor sleep). However, few longitudinal studies have examined risk factors of the natural history of poor sleep, and none have examined the role of polysomnographic (PSG) variables. Design: Representative longitudinal study. Setting: Sleep laboratory. Participants: From a random, general population sample of 1,741 individuals of the adult Penn State Cohort, 1,395 were followed up after 7.5 yr. Measurements: Full medical evaluation and 1-night PSG at baseline and telephone interview at follow-up. Results: The rate of incident poor sleep was 18.4%. Physical (e.g., obesity, sleep apnea, and ulcer) and mental (e.g., depression) health conditions and behavioral factors (e.g., smoking and alcohol consumption) increased the odds of incident poor sleep as compared to normal sleep. The rates of persistent, remitted, and poor sleepers who developed chronic insomnia were 39%, 44%, and 17%, respectively. Risk factors for persistent poor sleep were physical health conditions combined with psychologic distress. Shorter objective sleep duration and a family history of sleep problems were risk factors for poor sleep evolving into chronic insomnia. Conclusions: Poor sleep appears to be primarily a symptom of physical and mental health conditions, whereas the persistence of poor sleep is associated with psychologic distress. Importantly, sleep apnea appears to be associated with incident poor sleep but not with chronic insomnia. Finally, this study suggests that objective short sleep duration in poor sleepers is a biologic marker of genetic predisposition to chronic insomniaen_US
dc.description.sponsorshipThis research was funded in part by the National Institutes of Health grants RO1 51931, RO1 40916 (to Dr. Bixler), and RO1 64415 (to Dr. Vgontzas).en_US
dc.format.extent9 pag.es_ES
dc.format.mimetypeapplication/pdfen
dc.language.isoengen
dc.publisherAmerican Academy of Sleep Medicineen_US
dc.relation.ispartofSleepen_US
dc.rights© 2012 Associated Professional Sleep Societiesen_US
dc.subject.otherIncidenceen_US
dc.subject.otherPersistenceen_US
dc.subject.otherPoor sleepen_US
dc.subject.otherChronic insomniaen_US
dc.subject.otherPolysomnographyen_US
dc.titleClinical and polysomnographic predictors of the Natural History of poor sleep in the general populationen_US
dc.typearticleen
dc.subject.ecienciaMedicinaes_ES
dc.relation.publisherversionhttp://dx.doi.org/10.5665/sleep.1832es_ES
dc.identifier.doi10.5665/sleep.1832es_ES
dc.identifier.publicationfirstpage689es_ES
dc.identifier.publicationissue5es_ES
dc.identifier.publicationlastpage697es_ES
dc.identifier.publicationvolume35es_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
dc.rights.accessRightsopenAccessen
dc.authorUAMVela Bueno, Antonio (258967)
dc.facultadUAMFacultad de Medicina


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