The treatment of cartilage defects in the knee joint: Microfracture, mosaicplasty, and autologous chondrocyte implantation
Author
Rodríguez Merchán, E. CarlosEntity
UAM. Departamento de CirugíaPublisher
Frontline Medical Communications Inc.Date
2012Citation
The American Journal of Orthopedics 41.5 (2012): 236-239ISSN
1078-4519 (print); 1934-3418 (online)Subjects
Cartilage lesions; Stable knee; Well-aligned lower limb; MedicinaNote
Este artículo está disponible en la página web de la revista: http://www.amjorthopedics.comRights
© Quadrant HealthCom Inc. 2012. All rights reservedAbstract
The efficacy of microfracture (MF), mosaicplasty (MO),
and autologous chondrocyte implantation (ACI) techniques
are still a matter of debate. This review aims to
analyze comparative studies of these techniques, review
the results of no treatment, and the natural history of
untreated articular cartilage lesions.
A PubMed search on the topic was performed. The
most important (14) articles, as judged by the author,
were selected for this review.
There is limited evidence that any intervention significantly
alters the natural history of these lesions and
there is no evidence of significant difference between
ACI and MF and MO. Paramount for successful surgical
cartilage repair is a stable knee with a well-aligned lower
limb. There is insufficient evidence at present to say that
ACI is cost-effective, compared with MF or MO
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