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Use of reporter genes in the generation of vaccinia virus-derived vectors
dc.contributor.author | Ali, Sally Al | |
dc.contributor.author | Baldanta, Sara | |
dc.contributor.author | Fernández-Escobar, Mercedes | |
dc.contributor.author | Guerra García, María Susana | |
dc.contributor.other | UAM. Departamento de Medicina Preventiva y Salud Pública y Microbiología | es_ES |
dc.date.accessioned | 2017-04-21T16:51:17Z | |
dc.date.available | 2017-04-21T16:51:17Z | |
dc.date.issued | 2016-05-21 | |
dc.identifier.citation | Viruses 8.134 (2016): 1-18 | en_US |
dc.identifier.issn | 1999-4915 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10486/677998 | |
dc.description.abstract | Vaccinia virus (VACV) is one of the most extensively-studied viruses of the Poxviridae family. It is easy to genetically modify, so it has become a key tool for many applications. In this context, reporter genes facilitate the study of the role of foreign genes introduced into the genome of VACV. In this review, we describe the type of reporter genes that have been used to generate reporter-expressing VACV and the applications of the recombinant viruses obtained. Reporter-expressing VACV are currently employed in basic and immunology research, in the development of vaccines and cancer treatment. | en_US |
dc.description.sponsorship | This work is supported by Grant FIS2011-00127 and Reference SAF2014-54623-R to SG | en_US |
dc.format.extent | 18 pag. | es_ES |
dc.format.mimetype | application/pdf | en |
dc.language.iso | eng | en |
dc.publisher | MDPI AG | en_US |
dc.relation.ispartof | Viruses | en_US |
dc.rights | © 2016 by the authors; licensee MDPI, Basel, Switzerland. | es_ES |
dc.subject.other | Reporter-expressing virus | en_US |
dc.subject.other | Vaccine | en_US |
dc.subject.other | Vaccinia virus | en_US |
dc.title | Use of reporter genes in the generation of vaccinia virus-derived vectors | en_US |
dc.type | article | en |
dc.subject.eciencia | Medicina | es_ES |
dc.relation.publisherversion | http://dx.doi.org/10.3390/v8050134 | es_ES |
dc.identifier.doi | 10.3390/v8050134 | es_ES |
dc.identifier.publicationfirstpage | 1 | es_ES |
dc.identifier.publicationissue | 134 | es_ES |
dc.identifier.publicationlastpage | 18 | es_ES |
dc.identifier.publicationvolume | 8 | es_ES |
dc.relation.projectID | Gobierno de España. FIS2011-00127 | es_ES |
dc.relation.projectID | Gobierno de España. SAF2014-54623-R | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | en |
dc.rights.cc | Reconocimiento | es_ES |
dc.rights.accessRights | openAccess | es_ES |
dc.facultadUAM | Facultad de Medicina |