Hybrid experimental and model approaches for the caracterization of Lymnaea stagnalis neural activity. Part. II: Design and implementation of hybrid circuits in Lymnaea stagnalis

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dc.contributor.advisor Varona, Pablo (tutor)
dc.contributor.author Garrido Peña, Alicia
dc.contributor.other UAM. Departamento de Ingeniería Informática es_ES
dc.date.accessioned 2020-01-15T10:01:48Z
dc.date.available 2020-01-15T10:01:48Z
dc.date.issued 2019-12
dc.identifier.uri http://hdl.handle.net/10486/689812 en_US
dc.description Máster en Ingeniería Informática es_ES
dc.description.abstract Hybrid circuits bring together living and model neural activity, adapting each other into one unique circuit. This technique allows advanced studies of neural dynamics and the implementation of novel experimental protocols. In this project, a hybrid experiment has been designed to test the interaction of dynamic synapses and intrinsic neural properties such as subthreshold oscillations in shaping non-trivial responses to simple spike trains. For this purpose, a conductance-based model with subthreshold oscillations has been studied with this type of stimulation in order to run a prove-of-concept experiment to map input/output relationships. Moreover, it has been implemented in a real-time software tool, RTXI, to induce subthreshold oscillations into a quiescent living neuron and to perform the analysis in living neurons. This report also discusses additional validation experiments on this approach by using RTXI implementations in different scenarios. en_US
dc.format.extent 51 pág. es_ES
dc.format.mimetype application/pdf en_US
dc.language.iso eng en_US
dc.subject.other Hybrid circuits en_US
dc.subject.other Lymnaea Stagnalis en_US
dc.subject.other neural sequencies en_US
dc.title Hybrid experimental and model approaches for the caracterization of Lymnaea stagnalis neural activity. Part. II: Design and implementation of hybrid circuits in Lymnaea stagnalis en_US
dc.type masterThesis en_US
dc.subject.eciencia Informática es_ES
dc.rights.cc Reconocimiento – NoComercial – SinObraDerivada es_ES
dc.rights.accessRights openAccess en_US


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