dc.contributor.author | Palanisamy, Marimuthu | |
dc.contributor.author | Gil Ramírez, Alicia | |
dc.contributor.author | Ruiz Rodríguez, Alejandro | |
dc.contributor.author | Marín, Francisco R. | |
dc.contributor.author | Reglero Rada, Guillermo J. | |
dc.contributor.author | Soler Rivas, Cristina | |
dc.date.accessioned | 2014-02-17T18:46:58Z | |
dc.date.available | 2012-04-21 | |
dc.date.issued | 2012 | |
dc.identifier.citation | International Journal of Food Science & Technology 47.5 (2012): 1004-1010 | |
dc.identifier.issn | 0950-5423 (print) | |
dc.identifier.issn | 1365-2621 (online) | en_US |
dc.identifier.uri | http://hdl.handle.net/10486/9046 | |
dc.description | This is the peer reviewed version of the following article: Palanisamy, M. Testing edible mushrooms to inhibit the pancreatic lipase activity by an in vitro digestion model (2012) International Journal of Food Science and Technology, 47 (5), pp. 1004-1010., which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2621.2011.02934.x. This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving | en_US |
dc.description.abstract | One of the strategies in prevention or treatment of obesity is altering metabolism of lipids by inhibition of dietary fat absorption. The extracts obtained with methanol, water and methanol:water (1:1) from 21 mushroom species were screened as potential sources of pancreatic lipase (PL) inhibitors using a standardised in vitro test. Lepiota procera methanol:water (1:1) extracts showed the highest inhibition activity closely followed by Grifola frondosa, Pleurotus eryngii and Lyophyllum shimeji. Other mushroom strains such as Morchella conica, Marasmius oreades, Lentinula edodes, Amanita ponderosa and Boletus edulis also showed a certain inhibitory activity. However, when the PL inhibitory activity was evaluated using an in vitro digestion model mimicking gut conditions, none of the selected mushroom extracts were able to inhibit PL activity. On the contrary, stimulation of the lipase activity levels was observed and it was not due to endogenous mushroom lipases activities | en_US |
dc.description.sponsorship | The research was supported by the European Union within the 7th framework programme (7FM-PEOPLE-2009-IIF project 251285), ALIBIRD-CM S2009 ⁄AGR-1469 regional program from the Community of Madrid (Spain) and AGL2010-21537 national R+D program from the Spanish Ministry of Science and Innovation | en_US |
dc.format.extent | 7 pag. | es_ES |
dc.format.mimetype | application/pdf | |
dc.language.iso | eng | |
dc.publisher | Wiley | |
dc.relation.ispartof | International Journal of Food Science and Technology | en_US |
dc.rights | © 2012 The Authors | |
dc.rights | © 2012 Institute of Food Science and Technology | |
dc.subject | Lipasas | |
dc.subject.other | Fruiting bodies | en_US |
dc.subject.other | In vitro digestion | en_US |
dc.subject.other | Inhibitors | en_US |
dc.subject.other | Mushroom | en_US |
dc.subject.other | Pancreatic lipase | en_US |
dc.title | Testing edible mushrooms to inhibit the pancreatic lipase activity by an in vitro digestion model | |
dc.type | article | |
dc.subject.eciencia | Química | es_ES |
dc.type.review | Peer reviewed | |
dc.relation.publisherversion | http://dx.doi.org/10.1111/j.1365-2621.2011.02934.x | |
dc.identifier.doi | 10.1111/j.1365-2621.2011.02934.x | |
dc.identifier.publicationfirstpage | 1004 | |
dc.identifier.publicationissue | 5 | |
dc.identifier.publicationlastpage | 1010 | |
dc.identifier.publicationvolume | 47 | |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/FP7/251285 | en |
dc.relation.projectID | Comunidad de Madrid. S2009/AGR-1469/ALIBIRD | es_ES |
dc.relation.projectID | Gobierno de España. AGL2010-21537 | es_ES |
dc.type.version | info:eu-repo/semantics/acceptedVersion | en |
dc.rights.accessRights | openAccess | |
dc.authorUAM | Gil Ramírez, Alicia (264449) | |
dc.authorUAM | Palanisamy , Marimuthu (264591) | |
dc.facultadUAM | Facultad de Ciencias | |