The influence of puberty on vitamin D status in obese children and the possible relation between vitamin D deficiency and insulin resistance
Entidad
UAM. Departamento de Pediatría; Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD)Editor
De GruyterFecha de edición
2015-01-01Cita
10.1515/jpem-2014-0033
Journal of Pediatric Endocrinology and Metabolism 28.(1.2) 2015: 105-110
ISSN
0334-018X (print); 2191-0251 (on line)DOI
10.1515/jpem-2014-0033Versión del editor
http://dx.doi.org/10.1515/jpem-2014-0033Materias
Childhood obesity; Insulin resistance; Puberty; Vitamin D; MedicinaResumen
Background: Puberty can affect vitamin D levels.
Objectives: The goal of this study was to analyze the relation
between vitamin D deficiency and puberty in obese
Spanish children, along with the possible interrelation
between vitamin D status and degree of insulin resistance.
Methods: A cross-sectional study was carried out, in
which clinical and biochemical data were gathered from
120 obese and 50 normal weight children between January
2011 and January 2013.
Results: Mean vitamin D levels were 19.5 and 31.6 ng/mL
in obese pubertal and obese prepubertal children, respectively.
About 75% of the obese pubertal subjects and 46%
of the obese prepubertal subjects had vitamin D deficiency.
Vitamin D levels were significantly lower in pubescent subjects
compared with pre-pubescent subjects in summer,
fall, and winter. There was no apparent relation between
vitamin D levels and homeostasis model assessment index
for insulin resistence (expressed in standard deviation score
for sex and Tanner stage) in either puberty or pre-puberty.
Conclusion: Puberty may be a risk factor for the vitamin
D deficiency commonly found in the obese child population.
This deficiency is not associated with higher insulin
resistance in obese pubertal children compared with
obese prepubertal children
Lista de ficheros
Google Scholar:Gutiérrez Medina, Sonsoles
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Gavela Pérez, Teresa
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Domínguez-Garrido, María Nieves
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Gutiérrez-Moreno, Elisa
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Rovira, Adela
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Garcés, Carmen
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Soriano Guillén, Leandro
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