dc.contributor.author | Donat-Vargas, Carolina | |
dc.contributor.author | Sandoval-Insausti, Helena | |
dc.contributor.author | Peñalvo, José L. | |
dc.contributor.author | Moreno Iribas, Maria Concepción | |
dc.contributor.author | Amiano, Pilar | |
dc.contributor.author | Bes-Rastrollo, Maira | |
dc.contributor.author | Molina-Montes, Esther | |
dc.contributor.author | Moreno-Franco, Belén | |
dc.contributor.author | Agudo, Antonio | |
dc.contributor.author | Mayo, Cristina Lasheras | |
dc.contributor.author | Laclaustra, Martín | |
dc.contributor.author | De La Fuente Arrillaga, Carmen | |
dc.contributor.author | Chirlaque Lopez, Maria Dolores | |
dc.contributor.author | Sánchez, Maria José | |
dc.contributor.author | Martínez-Gonzalez, Miguel Angel | |
dc.contributor.author | Pilar, Guallar Castillón | |
dc.contributor.other | UAM. Departamento de Medicina Preventiva y Salud Pública y Microbiología | es_ES |
dc.date.accessioned | 2022-03-11T12:00:33Z | |
dc.date.available | 2022-03-11T12:00:33Z | |
dc.date.issued | 2021-12-03 | |
dc.identifier.citation | Clinical Nutrition 41.1 (2021): 122-130 | en_US |
dc.identifier.issn | 0261-5614 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10486/700741 | |
dc.description.abstract | Background & aims: The specific association of olive oil consumption with coronary heart disease (CHD) or stroke has not been totally established. Objective: to examine whether olive oil consumption is associated with subclinical atherosclerosis, the risk of total cardiovascular disease (CVD), CHD, and stroke. Methods: Three cohorts were included: AWHS (2318 men), SUN Project (18,266 men and women), and EPIC-Spain (39,393 men and women). Olive oil consumption was measured at baseline using validated questionnaires. Results: In the AWHS, 747 participants had a positive coronary artery calcium score (CACS>0), and the OR (95% CI) was 0.89 (0.72, 1.10) in those with virgin olive oil consumption ≥30 g/day (v. <10 g/day). In the SUN Project (follow-up 10.8 years) 261 total CVD cases occurred, and the HR was 0.57 (0.34, 0.96) for consumptions ≥30 g/day (v. <10 g/day). In the EPIC-Spain (follow-up 22.8 years) 1300 CHD cases and 938 stroke cases occurred; the HRs for stroke according, 0 to <10 (ref), 10 to <20, 20 to <30, and ≥30 g/day of olive oil consumption, were 0.84 (0.70, 1.02), 0.80 (0.66, 0.96), 0.89 (0.74, 1.07). A weaker association was observed for CHD. The association was stronger among those consuming virgin olive oil, instead of common (refined). Conclusions: Olive oil is associated with lower risk of CVD and stroke. The maximum benefit could be obtained with a consumption between 20 and 30 g/day. The association could be stronger for virgin olive oil and might operate from the early stages of the disease | en_US |
dc.description.sponsorship | FIS grants 17/1709, 20/144, PI20/00564 and PIE16/00022
(Instituto de Salud Carlos III, State Secretary of RþDþI, and FEDER/
FSE), PNSD (2020/021), the CIBERESP, the CIBERCV and CIBEROBN
(Instituto de Salud Carlos III). | en_US |
dc.format.extent | 9 pag. | es_ES |
dc.format.mimetype | application/pdf | en |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | en_US |
dc.relation.ispartof | Clinical Nutrition | en_US |
dc.rights | © 2021 The Authors | es_ES |
dc.subject.other | Cardiovascular disease | en_US |
dc.subject.other | Mediterranean countries | en_US |
dc.subject.other | Olive oil | en_US |
dc.subject.other | Primary prevention | en_US |
dc.subject.other | Stroke | en_US |
dc.subject.other | Subclinical atherosclerosis | en_US |
dc.title | Olive oil consumption is associated with a lower risk of cardiovascular disease and stroke | en_US |
dc.type | article | en_US |
dc.subject.eciencia | Medicina | es_ES |
dc.relation.publisherversion | https://doi.org/10.1016/j.clnu.2021.11.002 | es_ES |
dc.identifier.doi | 10.1016/j.clnu.2021.11.002 | es_ES |
dc.identifier.publicationfirstpage | 122 | es_ES |
dc.identifier.publicationissue | 1 | es_ES |
dc.identifier.publicationlastpage | 130 | es_ES |
dc.identifier.publicationvolume | 41 | es_ES |
dc.relation.projectID | Gobierno de España. FIS 17/1709 | es_ES |
dc.relation.projectID | Gobierno de España. FIS 20/144 | es_ES |
dc.relation.projectID | Gobierno de España. PI20/00564 | es_ES |
dc.relation.projectID | Gobierno de España. PIE16/00022 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | en |
dc.rights.cc | Reconocimiento – NoComercial – SinObraDerivada | |
dc.rights.accessRights | openAccess | es_ES |
dc.authorUAM | Donat Vargas, Carolina (314972) | |
dc.authorUAM | Laclaustra Gimeno, Martín (262750) | |
dc.authorUAM | Guallar Castillón, María Pilar (258415) | |
dc.facultadUAM | Facultad de Medicina | |
dc.institutoUAM | Instituto de Investigación Sanitaria Hospital Universitario de La Paz (IdiPAZ) | |