Effect of sex in systemic psoriasis therapy: Differences in prescription, effectiveness and safety in the BIOBADADERM prospective cohort
Entidad
UAM. Departamento de MedicinaEditor
Uppsala: Medical journals Sweden ABFecha de edición
2021-01-01Cita
10.2340/00015555-3711
Acta Dermato-Venereologica 101.1 (2021): adv00354
ISSN
0001-5555 (print); 1651-2057 (online)DOI
10.2340/00015555-3711Financiado por
The BIOBADADERM project is promoted by the Fundación Piel Sana Academia Española de Dermatología y Venereología, which receives financial support from the Spanish Medicines and Health Products Agency (Agencia Española de Medicamentos y Productos Sanitarios) and from pharmaceutical companies (Abbott/Abbvie, Pfizer, MSD, Novartis, Lilly, Janssen and Almirall).Materias
gender; sex; gender bias; sex bias; psoriasis; biological therapy; drug prescription; drug safety; MedicinaNota
"Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAM".Resumen
The effect of sex on systemic therapy for psoriasis has not been well studied. The aim of this study was to analyse a large multicentre Spanish cohort of 2,881 patients with psoriasis (58.3% males), followed from January 2008 to November 2018, to determine whether sex influences prescription, effectiveness of therapy, and the risk of adverse events. The results show that women are more likely than men to be pre-scribed biologics. There were no differences between men and women in effectiveness of therapy, measur-ed in terms of drug survival. Women were more likely to develop adverse events, but the difference in risk was small and does not justify different management. Study limitations include residual confounding and the use of drug survival as a proxy for effectiveness.
Lista de ficheros
Google Scholar:Hernández-Fernández, Carlos Pelayo
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Daudén Tello, Esteban
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BIOBADADERM Study Group
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