A MWCNTs-COOH/PSS nanocomposite–modified screen-printed electrode for the determination of synthetic phenolic antioxidants by HPLC with amperometric detection
Entity
UAM. Departamento de Química Analítica y Análisis InstrumentalPublisher
SpringerDate
2022-11-24Citation
10.1007/s00604-022-05552-7
Microchimica Acta 189 (2022): 469
ISSN
0026-3672 (print); 1436-5073 (online)DOI
10.1007/s00604-022-05552-7Funded by
Open Access funding provided thanks to the CRUE-CSIC agreement with Springer NatureEditor's Version
https://doi.org/10.1007/s00604-022-05552-7Subjects
Carbon nanotubes; Electrochemical detection; HPLC; Nanocomposites; Polystyrene sulfonate; Synthetic phenolic antioxidants; QuímicaRights
© The Author(s) 2022Abstract
New sensing platforms based on screen-printed carbon electrodes modifed with composites based on polystyrene sulfonate
and oxidized multi-walled carbon nanotubes (PSS/MWCNTs-COOH/SPCE) have been used to develop a novel HPLC method
with electrochemical detection (ECD) for the determination of the most used synthetic phenolic antioxidants in cosmetics:
butylhydroxytoluene (BHT), butylhydroxyanisole (BHA), tert-butylhydroquinone (TBHQ) and propyl gallate (PG). Optimal
separation conditions were achieved using methanol: 0.10 mol L−1 acetate solution at pH 6 as mobile phase with a gradient elution program from 60 to 90% of methanol percentage in 15 min. The electrochemical detection was carried out in
amperometric mode using the PSS/MWCNTs-COOH/SPCE at+0.80 V vs. Ag. Under these optimal separation and detection
conditions, the limits of detection (LOD) were between 0.11 and 0.25 mg L−1. These LOD values were better, especially
for BHT, than those previously published in other HPLC methods. Linear ranges from 0.37 mg L−1, 0.83 mg L−1, 0.69 mg
L−1 and 0.56 mg L−1 to 10 mg L−1 were obtained for PG, TBHQ, BHA and BHT, respectively. RSD values equal or lower
than 5% and 8% were achieved for repeatability and reproducibility, respectively. The HPLC-ECD method was successfully
applied to analyze diferent cosmetic samples. Recovery values within 83–109% were obtained in the validation studies
Files in this item
Google Scholar:Abad Gil, Lucía
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García Ríos, Mayte
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Isabel Cabrera, Carmen
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Gismera García, María Jesús
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Sevilla Escribano, M. Teresa
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Procopio, Jesús R.
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