Enantioselective Suzuki cross-coupling of 1,2-diboryl cyclopropanes
Entidad
UAM. Departamento de Química OrgánicaEditor
Royal Society of ChemistryFecha de edición
2023-01-13Cita
10.1039/d2sc05789a
Chemical Science 14.6 (2023):
ISSN
2041-6520 (print); 2041-6539 (online)DOI
10.1039/d2sc05789aProyecto
Gobierno de España. PID2019-107380GB-I00Versión del editor
https://doi.org/10.1039/d2sc05789aMaterias
Hydroboration; Alkene; Diborane; QuímicaDerechos
© 2023 The Author(s). Published by the Royal Society of ChemistryResumen
Herein, we describe the catalytic enantioselective cross-coupling of 1,2-bisboronic esters. Prior work on group specific cross coupling is limited to the use of geminal bis-boronates. This desymmetrization provides a novel approach to prepare enantioenriched cyclopropyl boronates with three contiguous stereocenters, that could be further derivatized through selective functionalization of the carbon-boron bond. Our results suggest that transmetallation, which is the enantiodetermining step, takes place with retention of stereochemistry at carbon
Lista de ficheros
Google Scholar:Teresa, Javier
-
Velado, Marina
-
Fernández de la Pradilla, Roberto
-
Viso, Alma
-
Lozano, Blanca
-
Tortosa Manzanares, Mariola
Lista de colecciones del ítem
Registros relacionados
Mostrando ítems relacionados por título, autor, creador y materia.