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dc.contributor.authorGonzález-Parra, Emilio
dc.contributor.authorGracia-Iguacel, Carolina
dc.contributor.authorEgido, Jesús
dc.contributor.authorOrtiz Arduán, Alberto 
dc.contributor.otherUAM. Departamento de Medicinaes_ES
dc.contributor.otherInstituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD)es_ES
dc.date.accessioned2014-07-03T11:40:42Z
dc.date.available2014-07-03T11:40:42Z
dc.date.issued2012-09-18
dc.identifier.citationInternational Journal of Nephrology 2012 (2012): 597605en_US
dc.identifier.issn2090-214Xes_ES
dc.identifier.urihttp://hdl.handle.net/10486/660717
dc.description.abstractPatients with renal impairment progressively lose the ability to excrete phosphorus. Decreased glomerular filtration of phosphorus is initially compensated by decreased tubular reabsorption, regulated by PTH and FGF23, maintaining normal serum phosphorus concentrations. There is a close relationship between protein and phosphorus intake. In chronic renal disease, a low dietary protein content slows the progression of kidney disease, especially in patients with proteinuria and decreases the supply of phosphorus, which has been directly related with progression of kidney disease and with patient survival. However, not all animal proteins and vegetables have the same proportion of phosphorus in their composition. Adequate labeling of food requires showing the phosphorus-to-protein ratio. The diet in patients with advanced-stage CKD has been controversial, because a diet with too low protein content can favor malnutrition and increase morbidity and mortality. Phosphorus binders lower serum phosphorus and also FGF23 levels, without decreasing diet protein content. But the interaction between intestinal dysbacteriosis in dialysis patients, phosphate binder efficacy, and patient tolerance to the binder could reduce their efficiency.en_US
dc.description.sponsorshipThe authors are supported by FIS PS09/00447, PI10/00072, EUS2008/03565, Fundacion Lilly, cvREMOD, ISCIII-RETIC REDinREN/RD06/0016, Comunidad de Madrid/CIFRA/SBIO0283/ 2006, S2010/BMD-2378, Sociedad Española de Nefrología, ERA-EDTA, Rio Hortega FIS and, Programa Intensificación Actividad Investigadora (ISCIII/Agencia Laın- Entralgo/CM) to A. Ortiz.en_US
dc.format.extent5 pag.es_ES
dc.format.mimetypeapplication/pdfes_ES
dc.language.isoenges_ES
dc.publisherHindawien_US
dc.relation.ispartofInternational Journal of Nephrologyes_ES
dc.rights© 2012 Emilio González-Parra et al.es_ES
dc.subject.otherKidneyen_US
dc.subject.otherNutritionen_US
dc.subject.otherPhosphorusen_US
dc.titlePhosphorus and nutrition in chronic kidney diseaseen_US
dc.typearticleen
dc.subject.ecienciaMedicinaes_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1155/2012/597605es_ES
dc.identifier.doi10.1155/2012/597605es_ES
dc.identifier.publicationfirstpage597605es_ES
dc.identifier.publicationvolume2012es_ES
dc.relation.projectIDComunidad de Madrid. S2010/BMD-2378/CIFRAes_ES
dc.relation.projectIDComunidad de Madrid. S2006/BIO-0283/FRACMes_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_ES
dc.rights.accessRightsopenAccessen
dc.facultadUAMFacultad de Medicina
dc.institutoUAMInstituto de Investigación Sanitaria Fundación Jiménez Díaz (ISS-FJD)


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