Toxic effects of mercury on the cardiovascular and central nervous systems
AuthorFernandes Azevedo, Bruna; Barros Furieri, Lorena; Peçanha, Franck MacIel; Wiggers, Giulia Alessandra; Frizera Vassallo, Paula; Ronacher Simões, Maylla; Fiorim, Jonaína; Rossi de Batista, Priscila; Fioresi, Mirian; Rossoni, Luciana Venturini; Stefanon, Ivanita; Alonso, María Jesús; Salaices Sánchez, Mercedes; Valentim Vassallo, Dalton
EntityUAM. Departamento de Farmacología
PublisherHindawi Publishing Corporation
10.1155/2012/949048Journal of Biomedicine and Biotechnology 2012 (2012): 949048
ISSN1110-7243 (print); 1110-7251 (online)
Funded byThese studies were supported by Grants from CAPES and CNPq/FAPES/FUNCITEC (39767531/07), Brazil and MCINN and MECD (SAF 2009-07201, RD06/0014/0011, and PHB2011-0001-PC) and Banco Santander, Spain
SubjectsBiological Transport; Cardiovascular System; Central Nervous System; Environmental Exposure; Mercury; Legislation as Topic; Medicina
RightsCopyright © 2012 Bruna Fernandes Azevedo et al.
Esta obra está bajo una Licencia Creative Commons Atribución 4.0 Internacional.
Environmental contamination has exposed humans to various metal agents, including mercury. This exposure is more common than expected, and the health consequences of such exposure remain unclear. For many years, mercury was used in a wide variety of human activities, and now, exposure to this metal from both natural and artificial sources is significantly increasing. Many studies show that high exposure to mercury induces changes in the central nervous system, potentially resulting in irritability, fatigue, behavioral changes, tremors, headaches, hearing and cognitive loss, dysarthria, incoordination, hallucinations, and death. In the cardiovascular system, mercury induces hypertension in humans and animals that has wide-ranging consequences, including alterations in endothelial function. The results described in this paper indicate that mercury exposure, even at low doses, affects endothelial and cardiovascular function. As a result, the reference values defining the limits for the absence of danger should be reduced
Google Scholar:Fernandes Azevedo, Bruna - Barros Furieri, Lorena - Peçanha, Franck MacIel - Wiggers, Giulia Alessandra - Frizera Vassallo, Paula - Ronacher Simões, Maylla - Fiorim, Jonaína - Rossi de Batista, Priscila - Fioresi, Mirian - Rossoni, Luciana Venturini - Stefanon, Ivanita - Alonso, María Jesús - Salaices Sánchez, Mercedes - Valentim Vassallo, Dalton
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