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dc.contributor.authorMavian, Carla Nartuhi
dc.contributor.authorLópez-Bueno, Alberto
dc.contributor.authorBalseiro, Ana
dc.contributor.authorCasáis, Rosa
dc.contributor.authorAlcamí, Antonio
dc.contributor.authorAlejo, Alí
dc.contributor.otherUAM. Departamento de Biología Moleculares_ES
dc.date.accessioned2015-02-09T13:17:42Z
dc.date.available2015-02-09T13:17:42Z
dc.date.issued2012-04-01
dc.identifier.citationJournal of Virology 86.7 (2012): 3617-3625en_US
dc.identifier.issn0022-538X (print)en_US
dc.identifier.issn1098-5514 (online)en_US
dc.identifier.urihttp://hdl.handle.net/10486/663675
dc.description.abstractWorldwide amphibian population declines have been ascribed to global warming, increasing pollution levels, and other factors directly related to human activities. These factors may additionally be favoring the emergence of novel pathogens. In this report, we have determined the complete genome sequence of the emerging common midwife toad ranavirus (CMTV), which has caused fatal disease in several amphibian species across Europe. Phylogenetic and gene content analyses of the first complete genomic sequence from a ranavirus isolated in Europe show that CMTV is an amphibian-like ranavirus (ALRV). However, the CMTV genome structure is novel and represents an intermediate evolutionary stage between the two previously described ALRV groups. We find that CMTV clusters with several other ranaviruses isolated from different hosts and locations which might also be included in this novel ranavirus group. This work sheds light on the phylogenetic relationships within this complex group of emerging, disease-causing viruses.en_US
dc.description.sponsorshipThis work was supported by grant AGL 2009-08711 from the Spanish Ministerio de Ciencia e Innovación. Alberto López-Bueno and Carla Mavián are recipients of the Ramón y Cajal and Formación del Personal Investigador fellowships, respectively, from the same institutiones_ES
dc.format.extent9 pag.en
dc.format.mimetypeapplication/pdfen
dc.language.isoengen
dc.publisherAmerican Society for Microbiologyen_US
dc.relation.ispartofJournal of Virologyen_US
dc.rights© 2014, American Society for Microbiologyen_US
dc.subject.otherGenomeen_US
dc.subject.otherVirusen_US
dc.subject.otherRanavirusesen_US
dc.titleThe genome sequence of the emerging common midwife toad virus identifies an evolutionary intermediate within ranavirusesen_US
dc.typearticleen
dc.subject.ecienciaBiología y Biomedicina / Biologíaes_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1128/JVI.07108-11es_ES
dc.identifier.doi10.1128/JVI.07108-11es_ES
dc.identifier.publicationfirstpage3617es_ES
dc.identifier.publicationissue7es_ES
dc.identifier.publicationlastpage3625es_ES
dc.identifier.publicationvolume86es_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
dc.rights.accessRightsopenAccessen
dc.facultadUAMFacultad de Ciencias
dc.institutoUAMCentro de Biología Molecular Severo Ochoa (CBMSO)


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