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The genome sequence of the emerging common midwife toad virus identifies an evolutionary intermediate within ranaviruses
dc.contributor.author | Mavian, Carla Nartuhi | |
dc.contributor.author | López Bueno, Alberto | |
dc.contributor.author | Balseiro, Ana | |
dc.contributor.author | Casáis, Rosa | |
dc.contributor.author | Alcamí, Antonio | |
dc.contributor.author | Alejo, Alí | |
dc.contributor.other | UAM. Departamento de Biología Molecular | es_ES |
dc.date.accessioned | 2015-02-09T13:17:42Z | |
dc.date.available | 2015-02-09T13:17:42Z | |
dc.date.issued | 2012-04-01 | |
dc.identifier.citation | Journal of Virology 86.7 (2012): 3617-3625 | en_US |
dc.identifier.issn | 0022-538X (print) | en_US |
dc.identifier.issn | 1098-5514 (online) | en_US |
dc.identifier.uri | http://hdl.handle.net/10486/663675 | |
dc.description.abstract | Worldwide amphibian population declines have been ascribed to global warming, increasing pollution levels, and other factors directly related to human activities. These factors may additionally be favoring the emergence of novel pathogens. In this report, we have determined the complete genome sequence of the emerging common midwife toad ranavirus (CMTV), which has caused fatal disease in several amphibian species across Europe. Phylogenetic and gene content analyses of the first complete genomic sequence from a ranavirus isolated in Europe show that CMTV is an amphibian-like ranavirus (ALRV). However, the CMTV genome structure is novel and represents an intermediate evolutionary stage between the two previously described ALRV groups. We find that CMTV clusters with several other ranaviruses isolated from different hosts and locations which might also be included in this novel ranavirus group. This work sheds light on the phylogenetic relationships within this complex group of emerging, disease-causing viruses. | en_US |
dc.description.sponsorship | This work was supported by grant AGL 2009-08711 from the Spanish Ministerio de Ciencia e Innovación. Alberto López-Bueno and Carla Mavián are recipients of the Ramón y Cajal and Formación del Personal Investigador fellowships, respectively, from the same institution | es_ES |
dc.format.extent | 9 pag. | en |
dc.format.mimetype | application/pdf | en |
dc.language.iso | eng | en |
dc.publisher | American Society for Microbiology | en_US |
dc.relation.ispartof | Journal of Virology | en_US |
dc.rights | © 2014, American Society for Microbiology | en_US |
dc.subject.other | Genome | en_US |
dc.subject.other | Virus | en_US |
dc.subject.other | Ranaviruses | en_US |
dc.title | The genome sequence of the emerging common midwife toad virus identifies an evolutionary intermediate within ranaviruses | en_US |
dc.type | article | en |
dc.subject.eciencia | Biología y Biomedicina / Biología | es_ES |
dc.relation.publisherversion | http://dx.doi.org/10.1128/JVI.07108-11 | es_ES |
dc.identifier.doi | 10.1128/JVI.07108-11 | es_ES |
dc.identifier.publicationfirstpage | 3617 | es_ES |
dc.identifier.publicationissue | 7 | es_ES |
dc.identifier.publicationlastpage | 3625 | es_ES |
dc.identifier.publicationvolume | 86 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | en |
dc.rights.accessRights | openAccess | en |
dc.facultadUAM | Facultad de Ciencias | |
dc.institutoUAM | Centro de Biología Molecular Severo Ochoa (CBMSO) |