Consensus statement on the diagnosis, management, and treatment of angioedema mediated by Bradykinin. Part. II: treatment, follow-up, and special situations
Entity
UAM. Departamento de MedicinaPublisher
Esmon PublicidadDate
2011Citation
Journal of Investigational Allergology and Clinical Immunology 21.6 (2011): 422-441ISSN
1018-9068 (print); 1698-0808 (online)Funded by
Dr. Teresa Caballero is a researcher with the Hospital La Paz Health Research Institute (IdiPaz) program for promoting research activities (2009)Subjects
Angiodema; C1 inhibidor; Bradicinina; Estrógenos; Inhibidores de la ECA; MedicinaRights
© 2011 Esmon PublicidadAbstract
Background: There are no previous Spanish guidelines or consensus statements on bradykinin-induced angioedema.
Aim: To draft a consensus statement on the management and treatment of angioedema mediated by bradykinin in light of currently available
scientifi c evidence and the experience of experts. This statement will serve as a guideline to health professionals.
Methods: The consensus was led by the Spanish Study Group on Bradykinin-Induced Angioedema, a working group of the Spanish Society
of Allergology and Clinical Immunology. A review was conducted of scientifi c papers on different types of bradykinin-induced angioedema
(hereditary and acquired angioedema due to C1 inhibitor defi ciency, hereditary angioedema related to estrogens, angioedema induced by
angiotensin-converting enzyme inhibitors). Several discussion meetings were held to reach the consensus.
Results: Treatment approaches are discussed, and the consensus reached is described. Specifi c situations are addressed, namely, pregnancy,
contraception, travelling, blood donation, and organ transplantation.
Conclusions: A review of and consensus on treatment of bradykinin-induced angioedema is presented Introducción: No existen guías previas españolas sobre el manejo del angioedema mediado por bradicinina.
Objetivos: Alcanzar un consenso sobre el manejo y tratamiento del angioedema mediado por bradicinina a la luz de la evidencia científi ca
disponible y la experiencia de los expertos, que sirva como guía para los profesionales de la salud.
Métodos: SGBA/GEAB, un grupo de trabajo de la SEAIC dirigió el consenso. Se realizó una revisión de los documentos científi cos publicados
sobre los diferentes tipos de angioedema mediado por bradicinina [angioedema hereditario o adquirido por defi ciencia de inhibidor de la
C1 esterasa, angioedema hereditario relacionado con estrógenos (AEH tipo III, AEH-FXII), angioedema inducido por IECA (inhibidores del
enzima convertidor de angiotensina]. Hubo varias reuniones del SGBA/GEAB para alcanzar el consenso.
Resultados: Se revisan y discuten los diferentes tratamientos disponibles y se describe el consenso alcanzado. Se abordan situaciones
específi cas (embarazo, anticoncepción, viajes, hemodonación, trasplante de órganos).
Conclusiones: Se presenta una revisión del tratamiento del angioedema mediado por bradicinina y un consenso sobre su tratamiento en
España
Files in this item
Google Scholar:Caballero, T.
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Baeza, M. L.
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Cabañas, R.
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Campos, A.
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Cimbollek, S.
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Gómez-Traseira, C.
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González-Quevedo, T.
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Guilarte, M.
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Jurado-Palomo, J.
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Larco, J. I.
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López-Serrano, M. C.
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López Trascasa, Margarita
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Marcos, C.
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Muñoz- Caro, J. M.
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Pedrosa, M.
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Prior, N.
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Rubio, M.
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Sala-Cunill, A.
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