Neural coding of tactile decisions in the human prefrontal cortex

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dc.contributor.author Pleger, Burkhard en_US
dc.contributor.author Ruff, Christian C. en_US
dc.contributor.author Blankenburg, Felix en_US
dc.contributor.author Bestmann, Sven en_US
dc.contributor.author Wiech, Katja en_US
dc.contributor.author Stephan, Klaas E. en_US
dc.contributor.author Capilla, Almudena es_ES
dc.contributor.author Friston, Karl J. en_US
dc.contributor.author Dolan, Raymond J. en_US
dc.contributor.other UAM. Departamento de Psicología Biológica y de la Salud es_ES
dc.date.accessioned 2015-11-11T17:25:48Z
dc.date.available 2015-11-11T17:25:48Z
dc.date.issued 2006-11-29
dc.identifier.citation The Journal of Neuroscience 26.48 (2006): 12596–12601 en_US
dc.identifier.issn 0270-6474 (print) en_US
dc.identifier.issn 1529-2401 (online) en_US
dc.identifier.uri http://hdl.handle.net/10486/668796 en_US
dc.description.abstract The neural processes underlying tactile decisions in thehumanbrain remain elusive.Weaddressed this question in a functional magnetic resonance imaging study using a somatosensory discrimination task, requiring participants to compare the frequency of two successive tactile stimuli. Tactile stimuli per se engaged somatosensory, parietal, and frontal cortical regions. Using a statistical model that accounted for the relative difference in frequencies (i.e., Weber fraction) and discrimination accuracy (i.e., correct or incorrect), we show that trial-by-trial relative frequency difference is represented linearly by activity changes in the left dorsolateral prefrontal cortex (DLPFC), the dorsal anterior cingulate cortex, and bilateral anterior insular cortices. However, a circumscribed region within the left DLPFC showed a different response pattern expressed as activity changes that were monotonically related to relative stimulation difference only for correct but not for incorrect trials. Our findings suggest that activity in the left DLPFC encodes stimulus representations that underlie veridical tactile decisions in humans. en_US
dc.format.extent 6 pag. es_ES
dc.format.mimetype application/pdf en_US
dc.language.iso eng en_US
dc.publisher Society for Neuroscience en_US
dc.relation.ispartof The Journal of Neuroscience en_US
dc.rights © 2006 Society for Neuroscience en_US
dc.subject.other Tactile decision en_US
dc.subject.other Tactile discrimination en_US
dc.subject.other Weber fraction en_US
dc.subject.other Somatosensory cortex en_US
dc.subject.other Dorsolateral prefrontal cortex en_US
dc.subject.other Functional magnetic resonance imaging en_US
dc.title Neural coding of tactile decisions in the human prefrontal cortex en_US
dc.type article en_US
dc.subject.eciencia Medicina es_ES
dc.subject.eciencia Psicología es_ES
dc.relation.publisherversion http://dx.doi.org/10.1523/JNEUROSCI.4275-06.2006 en_US
dc.identifier.doi 10.1523/JNEUROSCI.4275-06.2006 en_US
dc.identifier.publicationfirstpage 12596 es_ES
dc.identifier.publicationissue 48 es_ES
dc.identifier.publicationlastpage 12601 es_ES
dc.identifier.publicationvolume 26 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion en_US
dc.rights.cc Reconocimiento – NoComercial – CompartirIgual es_ES
dc.rights.accessRights openAccess en_US
dc.authorUAM Capilla González, Almudena (262256)


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