Selective carbohydrate-lectin interactions in covalent graphene- and SWCNT-based molecular recognition systems

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Show simple item record Ragoussi, Maria Eleni Casado, Santiago Ribeiro-Viana, Renato Rojo, Javier Torres, Tomás Torre, Gema de la
dc.contributor.other UAM. Departamento de Química Orgánica es_ES 2016-05-26T15:03:22Z 2016-05-26T15:03:22Z 2013-07-19
dc.identifier.citation Chemical Science 4.10 (2013): 4035-4041 en_US
dc.identifier.issn 2041-6520 (print) es_ES
dc.identifier.issn 2041-6539 (online) es_ES
dc.description.abstract Two new protein recognition systems have been prepared by covalent functionalization of few-layer graphene and SWCNTs with α-d-mannosyl dendrons. A glycodendron, bearing three mannose moieties on the periphery for effective interaction with the lectin, and an azido group at the focal position, has been connected, by means of a "click" chemistry reaction, to both few-layer graphene and SWCNTs endowed with terminal ethynyl groups. The specific affinity of these systems for concanavalin A was thoroughly investigated by AFM, fluorescence and UV-Vis studies. A very reliable approach was used during the AFM investigation of this kind of hybrids; namely, we were able to capture the same object before and after treatment with ConA, which allowed us to obtain reliable conclusions, in terms of selectivity of the carbohydrate-lectin interactions over the nanocarbon platforms en_US
dc.description.sponsorship Financial support is acknowledged from the Spanish MICINN (CTQ2011-24187/BQU, CTQ2011-23410/BQU and CONSOLIDER INGENIO 2010, CSD2007-00010 on Molecular Nanoscience) and the Comunidad de Madrid (MADRISOLAR-2, S2009/PPQ/1533). Thanks to the subscription of Red de Bibliotecas del CSIC to the RSC Gold for Gold Application for getting open access for this article en_US
dc.format.extent 7 pag. es_ES
dc.format.mimetype application/pdf en
dc.language.iso eng en
dc.publisher The Royal Society of Chemistry en_US
dc.relation.ispartof Chemical Science en_US
dc.rights © 2013 The Royal Society of Chemistry en_US
dc.subject.other After-treatment en_US
dc.subject.other Carbohydrate-lectin interactions en_US
dc.subject.other Covalent functionalizations en_US
dc.subject.other Effective interactions en_US
dc.subject.other Few-layer graphene en_US
dc.subject.other Focal positions en_US
dc.subject.other Molecular recognition systems en_US
dc.subject.other Protein recognition en_US
dc.title Selective carbohydrate-lectin interactions in covalent graphene- and SWCNT-based molecular recognition systems en_US
dc.type article en
dc.subject.eciencia Química es_ES
dc.relation.publisherversion es_ES
dc.identifier.doi 10.1039/c3sc51352a es_ES
dc.identifier.publicationfirstpage 4035 es_ES
dc.identifier.publicationissue 10 es_ES
dc.identifier.publicationlastpage 4041 es_ES
dc.identifier.publicationvolume 4 es_ES
dc.relation.projectID Gobierno de España. CTQ2011-24187/BQU es_ES
dc.relation.projectID Gobierno de España. CTQ2011-23410/BQU es_ES
dc.relation.projectID Gobierno de España. CSD2007-00010 es_ES
dc.relation.projectID Comunidad de Madrid. S2009/PPQ/1533/MADRISOLAR-2 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion en Reconocimiento – NoComercial es_ES
dc.rights.accessRights openAccess en
dc.authorUAM Ragoussi , María Eleni (264423)

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