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dc.contributor.authorBraido, Fulvio
dc.contributor.authorBrusselle, Guy
dc.contributor.authorGuastalla, Daniele
dc.contributor.authorIngrassia, Eleonora
dc.contributor.authorNicolini, Gabriele
dc.contributor.authorPrice, David
dc.contributor.authorRoche, Nicolás
dc.contributor.authorSoriano, Joan B.
dc.contributor.authorWorth, Heinrich
dc.contributor.authorLIAISON Study Group
dc.contributor.otherUAM. Departamento de Medicinaes_ES
dc.contributor.otherInstituto de Investigación del Hospital de La Princesa (IP)es_ES
dc.date.accessioned2017-04-28T11:04:13Z
dc.date.available2017-04-28T11:04:13Z
dc.date.issued2016-05-14
dc.identifier.citationRespiratory Research 17.1 (2016): 51en_US
dc.identifier.issn1465-9921 (print)es_ES
dc.identifier.issn1465-993X (online)es_ES
dc.identifier.urihttp://hdl.handle.net/10486/678058
dc.description.abstractBackground: According to the Global Initiative of Asthma, the aim of asthma treatment is to gain and maintain control. In the INTERNATIONAL CROSS-SECTIONAL AND LONGITUDINAL ASSESSMENT ON ASTHMA CONTROL (LIAISON) study, we evaluated the level of asthma control and quality of life (QoL), as well as their determinants and impact in a population consulting specialist settings. Methods: LIAISON is a prospective, multicentre, observational study with a cross-sectional and a 12-month longitudinal phase. Adults with an asthma diagnosis since at least 6 months, receiving the same asthma treatment in the 4 weeks before enrolment were included. Asthma control was assessed with the 6-item Asthma Control Questionnaire (ACQ) and QoL with the MiniAsthma Quality of Life Questionnaire (MiniAQLQ). Results: Overall, 8111 asthmatic patients were enrolled in 12 European countries. Asthma control was suboptimal in 56.5 % of patients and it was associated with poorer asthma-related QoL, higher risk of exacerbations and greater consumption of healthcare resources. Variables associated with suboptimal control were age, gender, obesity, smoking and comorbidities. Major determinants of poor asthma control were seasonal worsening and persisting exposure to allergens/irritants/triggers, followed by treatment-related issues. Conclusions: The cross-sectional phase results confirm that suboptimal control is frequent and has a high individual and economic impact. Trial registration: The clinicaltrials.gov identifier is NCT01567280.en_US
dc.format.extent10 pag.es_ES
dc.format.mimetypeapplication/pdfen
dc.language.isoengen
dc.publisherBioMed Centralen_US
dc.relation.ispartofRespiratory Researchen_US
dc.rights© 2016 Braido et ales_ES
dc.subject.otherAsthma controlen_US
dc.subject.otherQuality of Lifeen_US
dc.subject.otherLiaisonen_US
dc.subject.otherSuboptimal controles_ES
dc.titleDeterminants and impact of suboptimal asthma control in Europe: The International Cross-Sectional and Longitudinal Assessment on Asthma Control (Liaison) studyen_US
dc.typearticleen
dc.subject.ecienciaMedicinaes_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1186/s12931-016-0374-zes_ES
dc.identifier.doi10.1186/s12931-016-0374-zes_ES
dc.identifier.publicationfirstpage51-1es_ES
dc.identifier.publicationissue1es_ES
dc.identifier.publicationlastpage51-10es_ES
dc.identifier.publicationvolume17es_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
dc.rights.ccReconocimientoes_ES
dc.rights.accessRightsopenAccessen
dc.facultadUAMFacultad de Medicina
dc.institutoUAMInstituto de Investigación Sanitaria Hospital Universitario de La Princesa (IIS-Princesa)


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