Emergence of an abstract categorical code enabling the discrimination of temporally structured tactile stimuli
EntityUAM. Departamento de Física Teórica
PublisherNational Academy of Sciences
10.1073/pnas.1618196113Proceedings of the National Academy of Sciences of the United States of America 113.49 (2016): E7966-E7975
ISSN0027-8424 (print); 1091-6490 (online)
Funded byThis work was supported in part by the Dirección de Asuntos del Personal Académico de la Universidad Nacional Autónoma de México and Consejo Nacional de Ciencia y Tecnología (R.R.) and Grant FIS2015-67876-P (to N.P.)
ProjectGobierno de España. FIS2015-67876-P
SubjectsBehaving monkeys; Categorical code; Dorsal premotor cortex; Pattern discrimination; Somatosensory cortex; Física
The problem of neural coding in perceptual decision making revolves around two fundamental questions: (i) How are the neural representations of sensory stimuli related to perception, and (ii) what attributes of these neural responses are relevant for downstream networks, and how do they influence decision making? We studied these two questions by recording neurons in primary somatosensory (S1) and dorsal premotor (DPC) cortex while trained monkeys reported whether the temporal pattern structure of two sequential vibrotactile stimuli (of equal mean frequency) was the same or different. We found that S1 neurons coded the temporal patterns in a literal way and only during the stimulation periods and did not reflect the monkeys' decisions. In contrast, DPC neurons coded the stimulus patterns as broader categories and signaled them during the working memory, comparison, and decision periods. These results show that the initial sensory representation is transformed into an intermediate, more abstract categorical code that combines past and present information to ultimately generate a perceptually informed choice
Google Scholar:Rossi-Pool, R. - Salinas, E. - Zainos, A. - Alvarez, M. - Vergara, J. - Parga Carballeda, Néstor - Romo, R.
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