Biofunctional porous silicon micropatterns engineered through visiblelight activated epoxy capping and selective plasma etching
Entity
UAM. Departamento de Física Aplicada; UAM. Instituto Universitario de Ciencia de Materiales Nicolás Cabrera (INC); UAM. Centro de Microanálisis de Materiales (CMAM)Publisher
Elsevier Ltd.Date
2018-02-06Citation
10.1016/j.vacuum.2018.01.045
Vacuum 150 (2018): 232-238
ISSN
0042-207X (print); 1879-2715 (online)DOI
10.1016/j.vacuum.2018.01.045Funded by
We acknowledge MSC funding provided by the European Commission through FPVII grant THINFACE(ITN GA 607232).Project
info:eu-repo/grantAgreement/EC/FP7/607232Editor's Version
http://doi.org/10.1016/j.vacuum.2018.01.045Subjects
Porous silicon; Organosilanes; Biofunctional particles; Solid state NMR; Surface functionalization; FísicaRights
© 2018 Elsevier Ltd.Esta obra está bajo una licencia de Creative Commons Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional.
Abstract
Porous silicon (PSi) is a versatile matrix with tailorable surface reactivity, which allows processing adiversity of biofunctional structures. An assembly process has been activated by catalyzing PSi oxidationwith visible light, enabling subsequent binding with (3-glycidyloxypropyl)-trimethoxy-silane (GPTMS) inthe submonolayer regime. A multispectroscopic approach has been followed to fully characterize thesurface capped PSi. XPS has been used to trace the process of light induced oxidation and GPTMS as-sembly on supported PSi. Field emission SEM confirms that the surface topography is not modified by theactivated assembly. To complement the chemical analysis of the bound GPTMS, FTIR and solid state NMRwere used on functionalized PSi particles. Finally, the surfaces of GPTMS capped PSi have been suc-cessfully micropatterned by a masked Ar plasma etching process. The process gives rise to surface hy-drophilic/hydrophobic contrasts, which are efficient in the selective binding of activated goldnanoparticles. The contrasts were applied to the local recognition of mouse serum proteins adsorbed onGPTMS functionalized PSi through an immunofluorescence assay. The results confirm the effectiveness ofGPTMS capped PSi as adsorptive layer for immunosensing
Files in this item
Google Scholar:Rodríguez, C.
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Ahumada, O.
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Cebrián, V.
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Torres Costa, Vicente
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Manso Silván, Miguel
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