Cyto- and myelo-architecture of the amygdaloid complex of the common marmoset monkey (Callithrix jacchus)
EntityUAM. Departamento de Anatomía, Histología y Neurociencia
PublisherFrontiers Media S.A.
10.3389/fnana.2019.00036Frontiers in Neuroanatomy 13.March (2019): 36
Funded byThis work was supported by funding from the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq-Brazil) Programa de Ciencia sem Fronteiras—Pesquisador Visitante Especial 024.028/2017, PVE 2014 and 400730/2014-6, PVE 2014 and by a grant from the Ministerio de Educación y Cultura, programa hispano brasileño de cooperación interuniversitaria, PHB H2012-0011 (Spain).
ProjectGobierno de España. PHB H2012-0011
SubjectsAmygdaloid complex; Marmoset Callithrix jacchus; Myelin staining; Nuclear division; Tractography; Medicina
Rights© 2019 Araújo Góis Morais, García-Amado, Lima, Córdoba-Claros, Souza Cavalcante, Clascá and Nascimento
Esta obra está bajo una Licencia Creative Commons Atribución 4.0 Internacional.
The amygdaloid complex (AC) is a heterogeneous aggregate of nuclei located in the rostromedial region of the temporal lobe. In addition to being partly connected among themselves, the AC nuclei are strongly interconnected with the cerebral cortex, striatum, basal forebrain, hypothalamus and brainstem. Animal and human functional studies have established that the AC is a central hub of the neuronal networks supporting emotional responsivity, particularly its negative/aversive components. Dysfunction of AC circuits in humans has been implicated in anxiety, depression, schizophrenia and bipolar disorder. The small New-World marmoset monkey (Callithrix jacchus) has recently become a key model for neuroscience research. However, the nuclear and fiber tract organization of marmoset AC has not been examined in detail. Thus, the extent to which it can be compared to the AC of Old-World (human and macaque) primates is yet unclear. Here, using Nissl and acetylcholinesterase (AChE) histochemical stains as a reference, we analyzed the cytoarchitecture and nuclear parcellation of the marmoset AC. In addition, given the increasing relevance of tractographic localization for high-resolution in vivo imaging studies in non-human primates, we also identified the myelin fiber tracts present within and around the AC as revealed by the Gallyas method. The present study provides a detailed atlas of marmoset AC. Moreover, it reveals that, despite phylogenetic distance and brain size differences, every nucleus and myelinated axon bundle described in human and macaque studies can be confidently recognized in marmosets.
Google Scholar:Araújo Góis Morais, Paulo Leonardo - García-Amado, María - Lima, Ruthnaldo Rodrigues Melo - Córdoba-Claros, Angélica - Souza Cavalcante, Jeferson - Clascá, Francisco - Nascimento, Expedito Silva
This item appears in the following Collection(s)
Showing items related by title, author, creator and subject.