Plasmonic Copper Sulfide Nanoparticles Enable Dark Contrast in Optical Coherence Tomography

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Show simple item record Marin, Riccardo Lifante, José Besteiro, Lucas V. Wang, Zhiming Govorov, Alexander O. Rivero, Fernando Alfonso, Fernando Sanz-Rodríguez, Francisco Jaque, Daniel
dc.contributor.other UAM. Departamento de Física de Materiales es_ES 2020-03-09T11:45:12Z 2020-03-09T11:45:12Z 2020-01-01
dc.identifier.citation Advanced Healthcare Materials 2020 9.5 (2020): 1901627 en_US
dc.identifier.issn 2192-2659 (online) en_US
dc.identifier.issn 2192-2640 (print) en_US
dc.description This is the peer reviewed version of the following article: Marin, R., Lifante, J., Besteiro, L. V., Wang, Z., Govorov, A. O., Rivero, F., ... & Jaque, D. (2020). Plasmonic Copper Sulfide Nanoparticles Enable Dark Contrast in Optical Coherence Tomography. Advanced Healthcare Materials 2020 9.5 (2020): 1901627, which has been published in final form at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions en_US
dc.description.abstract Optical coherence tomography (OCT) is an imaging technique affording noninvasive optical biopsies. Like for other imaging techniques, the use of dedicated contrast agents helps better discerning biological features of interest during the clinical practice. Although bright OCT contrast agents have been developed, no dark counterpart has been proposed yet. Herein, plasmonic copper sulfide nanoparticles as the first OCT dark contrast agents working in the second optical transparency window are reported. These nanoparticles virtually possess no light scattering capabilities at the OCT working wavelength (≈1300 nm); thus, they exclusively absorb the probing light, which in turn results in dark contrast. The small size of the nanoparticles and the absence of apparent cytotoxicity support the amenability of this system to biomedical applications. Importantly, in the pursuit of systems apt to yield OCT dark contrast, a library of copper sulfide nanoparticles featuring plasmonic resonances spanning the three optical transparency windows is prepared, thus highlighting the versatility and potential of these systems in light-controlled biomedical applications en_US
dc.description.sponsorship This project was partially funded by the European Commission through the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant agreement No. 797945 “LANTERNS”. This work was partially supported by the Ministerio de Economía y Competitividad de España (MAT2016-75362-C3-1-R) and (MAT2017-83111R), by the Instituto de Salud Carlos III (PI16/00812), by the Comunidad Autónoma de Madrid (B2017/BMD-3867RENIMCM), and co-financed by the European Structural and investment fund. Additional funding was provided by the European Commission Horizon 2020 project NanoTBTech. L.V.B was supported by the Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China and China Postdoctoral Science Foundation (2017M622992 and 2019T120820). Z.W. was supported by the National Basic Research Program of China (Project 2013CB933301) and the National Natural Science Foundation of China (Project 51272038). A.G. was funded via the 1000-talent Award of Sichuan and by the Volkswagen Foundation. Prof. Jorge Rubio-Retama is gratefully acknowledged for granting access to the dynamic light scattering instrument and for the fruitful discussion en_US
dc.format.extent 41 pag. en_US
dc.format.mimetype application/pdf en
dc.language.iso eng en
dc.publisher Wiley-VCH Verlag en_US
dc.relation.ispartof Advanced Healthcare Materials en_US
dc.rights © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim en_US
dc.subject.other Contrast agents en_US
dc.subject.other Copper sulfide en_US
dc.subject.other Optical transparency windows en_US
dc.subject.other Optical-coherence tomography en_US
dc.subject.other Plasmonic nanoparticles en_US
dc.title Plasmonic Copper Sulfide Nanoparticles Enable Dark Contrast in Optical Coherence Tomography en_US
dc.type article en
dc.subject.eciencia Física es_ES 2021-03-04
dc.relation.publisherversion es_ES
dc.identifier.doi 10.1002/adhm.201901627 es_ES
dc.identifier.publicationfirstpage 1901627-1 es_ES
dc.identifier.publicationissue 5 es_ES
dc.identifier.publicationlastpage 1901627-10 es_ES
dc.identifier.publicationvolume 9 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/797945/EU//LANTERNS en_US
dc.relation.projectID Gobierno de España. MAT2016-75362-C3-1-R es_ES
dc.relation.projectID Gobierno de España. MAT2017-83111-R es_ES
dc.relation.projectID Comunidad de Madrid. B2017/BMD-3867/RENIM-CM es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/801305/EU//NanoTBTech en_US
dc.type.version info:eu-repo/semantics/acceptedVersion en
dc.rights.accessRights openAccess en
dc.authorUAM Sanz Rodríguez, Francisco (260710)
dc.authorUAM Jaque García, Daniel (261194)

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