Show simple item record

dc.contributor.authorLópez-Márquez, Arístides
dc.contributor.authorAlonso-Barroso, Esmeralda
dc.contributor.authorCerro-Tello, Gema
dc.contributor.authorBravo-Alonso, I.
dc.contributor.authorArribas-Carreira, L.
dc.contributor.authorBriso-Montiano, Álvaro
dc.contributor.authorNavarrete, Rosa
dc.contributor.authorPérez-Cerdá, C.
dc.contributor.authorUgarte, Magdalena
dc.contributor.authorPérez, Belén
dc.contributor.authorRuiz Desviat, Lourdes 
dc.contributor.authorRichard Rodríguez, Eva María 
dc.contributor.otherUAM. Departamento de Biología Moleculares_ES
dc.date.accessioned2020-05-04T08:38:21Z
dc.date.available2020-05-04T08:38:21Z
dc.date.issued2019-08-01
dc.identifier.citationStem Cell Research 2019.39 (2019): 101516en_US
dc.identifier.issn1873-5061
dc.identifier.urihttp://hdl.handle.net/10486/690956
dc.description.abstractWe have generated and characterized seven human induced pluripotent stem cell (iPSC) lines derived from peripheral blood mononuclear cells (PBMCs) from a single family, including unaffected and affected individuals clinically diagnosed with Autism Spectrum Disorder (ASD). The reprogramming of the PBMCs was performed using non-integrative Sendai virus containing the reprogramming factors POU5F1 (OCT4), SOX2, KLF4 and MYC. All iPSC lines exhibited a normal karyotype and pluripotency was validated by immunofluorescence, flow cytometry and their ability to differentiate into the three embryonic germ layers. These iPSC lines are a valuable resource to study the molecular mechanisms underlying ASDen_US
dc.description.sponsorshipThis study was funded in part by the Australian National Health and Medical Research Council (NHMRC) project grants (GNT1044175 and GNT1098255) awarded to E.G.S, M.B.D, I.S and P.J.L. K.B is supported by an E.H. Flack Fellowship and P.J.L is supported by the Vincent Chiodo Foundation. Additional infrastructure funding to the Murdoch Children's Research Institute was provided by the Australian Government NHMRC Independent Research Institute Infrastructure Support Scheme and the Victorian Government's Operational Infrastructure Support Program. The MCRI iPSC Core Facility is supported by the Stafford Fox Medical Research Foundation. M.B and E.G.S are Research Fellows, and I.S is a Practitioner Fellow, of the NHMRCen_US
dc.format.extent5 pag.en_US
dc.format.mimetypeapplication/pdfen
dc.language.isoengen
dc.publisherElsevier BVen_US
dc.relation.ispartofStem Cell Researchen_US
dc.rights© 2019 The Author(s)en_US
dc.subject.otherMononuclear cellsen_US
dc.subject.otherPeripheral blood mononuclear cells (PBMCs)en_US
dc.subject.otherAutism Spectrum Disorder (ASD)en_US
dc.titleCorrigendum to “Generation and characterization of a human iPSC line (UAMi004-A) from a patient with propionic acidemia due to defects in the PCCB gene”es_ES
dc.typearticleen
dc.subject.ecienciaBiología y Biomedicina / Biologíaes
dc.relation.publisherversionhttps://doi.org/10.1016/j.scr.2019.101516
dc.identifier.doi10.1016/j.scr.2019.101513
dc.identifier.publicationfirstpage101516-1
dc.identifier.publicationissue39
dc.identifier.publicationlastpage101516-5
dc.identifier.publicationvolume2019
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
dc.rights.ccReconocimientoes_ES
dc.rights.accessRightsopenAccessen
dc.authorUAMAlonso Barroso, Esmeralda (278926)
dc.authorUAMLópez Márquez, Aristides (264909)
dc.authorUAMNavarrete Martín, Rosa María (264439)
dc.authorUAMUgarte Pérez, Magdalena (259473)
dc.authorUAMRuiz Desviat, Lourdes (260916)
dc.authorUAMRichard Rodríguez, Eva María (260198)
dc.facultadUAMFacultad de Ciencias
dc.institutoUAMCentro de Biología Molecular Severo Ochoa (CBMSO)


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record