Universidad Autónoma de Madrid

Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imaging

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Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imaging

Metadatos
Title: Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imaging
Author: Nuñez, Nuria O.; Cussó, Fernando; Cantelar, Eugenio; Martin-gracia, Beatriz; de la Fuente, Jesús M.; Corral, Ariadna; Balcerzyk, Marcin; Ocaña, Manuel
Entity: UAM. Departamento de Física de Materiales
UAM Author: Cussó Pérez, Fernando ; Cantelar Alcaide, Eugenio Francisco
Publisher: M D P I AG
Date: 2020-01-01
Citation: Nanomaterials 10.1 (2020): 149
ISSN: 2079-4991
DOI: 10.3390/nano10010149
Funded by: This work has been supported by the Spanish Ministry of Science, Innovation and Universities (MCIU/AEI/FEDER) under grant RTI2018-094426-B-I00, and Ministerio de Economía y Competitividad (MINECO) under project MAT2016-75716-C2-2-R
Project: Gobierno de España. RTI2018-094426-B-I00; Gobierno de España. MAT2016-75716-C2-2-R
Editor's Version: https://doi.org/10.3390/nano10010149
Subjects: LuVO4; Nanoparticles; Neodymium; NIR luminescence; Polyacrilic acid; X-ray computed tomography; Física
URI: http://hdl.handle.net/10486/691082
Rights: © 2020 by the authors

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Esta obra está bajo una Licencia Creative Commons Atribución 4.0 Internacional.

Abstract:

Uniform Nd3+-doped LuVO4 nanophosphors have been synthesized for the first time in literature by using a poliol-based method at 120 °C from Nd3+ and vanadate precursors. After optimizing the Nd doping level, these phosphors present intense luminescence in the near-infrared biological windows. The X-ray attenuation capacity of the optimum nanophosphor has been found to be higher than that of a commercial X-ray computed tomography contrast agent. After surface coating with polyacrylic acid, such nanoparticles present high colloidal stability in physiological pH medium and high cell viability. Because of these properties, the developed Nd3+-doped LuVO4 nanoparticles have potential applications as a bimodal probe for NIR luminescent bioimaging and X-ray computed tomography

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Citations
G o o g l e ™ Scholar: Nuñez, Nuria O. - Cussó, Fernando - Cantelar, Eugenio - Martin-gracia, Beatriz - de la Fuente, Jesús M. - Corral, Ariadna - Balcerzyk, Marcin - Ocaña, Manuel

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