Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imaging
Entity
UAM. Departamento de Física de MaterialesPublisher
M D P I AGDate
2020-01-01Citation
10.3390/nano10010149
Nanomaterials 10.1 (2020): 149
ISSN
2079-4991DOI
10.3390/nano10010149Funded by
This work has been supported by the Spanish Ministry of Science, Innovation and Universities (MCIU/AEI/FEDER) under grant RTI2018-094426-B-I00, and Ministerio de Economía y Competitividad (MINECO) under project MAT2016-75716-C2-2-RProject
Gobierno de España. RTI2018-094426-B-I00; Gobierno de España. MAT2016-75716-C2-2-REditor's Version
https://doi.org/10.3390/nano10010149Subjects
LuVO4; Nanoparticles; Neodymium; NIR luminescence; Polyacrilic acid; X-ray computed tomography; FísicaRights
© 2020 by the authorsAbstract
Uniform Nd3+-doped LuVO4 nanophosphors have been synthesized for the first time in literature by using a poliol-based method at 120 °C from Nd3+ and vanadate precursors. After optimizing the Nd doping level, these phosphors present intense luminescence in the near-infrared biological windows. The X-ray attenuation capacity of the optimum nanophosphor has been found to be higher than that of a commercial X-ray computed tomography contrast agent. After surface coating with polyacrylic acid, such nanoparticles present high colloidal stability in physiological pH medium and high cell viability. Because of these properties, the developed Nd3+-doped LuVO4 nanoparticles have potential applications as a bimodal probe for NIR luminescent bioimaging and X-ray computed tomography
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Google Scholar:Nuñez, Nuria O.
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Cussó, Fernando
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Cantelar, Eugenio
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Martin-gracia, Beatriz
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de la Fuente, Jesús M.
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Corral, Ariadna
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Balcerzyk, Marcin
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Ocaña, Manuel
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