dc.contributor.author | López-Moriñigo, Javier-David | |
dc.contributor.author | González Ruiz-Ruano, Verónica | |
dc.contributor.author | Sánchez Escribano Martínez, Adela | |
dc.contributor.author | Barrigón Estévez, María Luisa | |
dc.contributor.author | Mata-Iturralde, Laura | |
dc.contributor.author | Muñoz-Lorenzo, Laura | |
dc.contributor.author | Sánchez-Alonso, Sergio | |
dc.contributor.author | Artés-Rodríguez, Antonio | |
dc.contributor.author | David, Anthony S. | |
dc.contributor.author | Baca García, Enrique | |
dc.contributor.other | UAM. Departamento de Psiquiatría | es_ES |
dc.contributor.other | Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD) | es_ES |
dc.date.accessioned | 2020-12-18T08:10:50Z | |
dc.date.available | 2020-12-18T08:10:50Z | |
dc.date.issued | 2020-01-29 | |
dc.identifier.citation | BMC Psychiatry 20 (2020): 30 | en_US |
dc.identifier.issn | 1471-244X | es_ES |
dc.identifier.uri | http://hdl.handle.net/10486/692760 | |
dc.description.abstract | Background: Although insight in schizophrenia spectrum disorders (SSD) has been associated with positive
outcomes, the effect size of previous treatments on insight has been relatively small to date. The metacognitive
basis of insight suggests that metacognitive training (MCT) may improve insight and clinical outcomes in SSD,
although this remains to be established.
Methods: This single-center, assessor-blind, parallel-group, randomised clinical trial (RCT) aims to investigate the
efficacy of MCT for improving insight (primary outcome), including clinical and cognitive insight, which will be
measured by the Schedule for Assessment of Insight (Expanded version) (SAI-E) and the Beck Cognitive Scale (BCIS),
respectively, in (at least) n = 126 outpatients with SSD at three points in time: i) at baseline (T0); ii) after treatment
(T1) and iii) at 1-year follow-up (T2). SSD patients receiving MCT and controls attending a non-intervention support
group will be compared on insight level changes and several clinical and cognitive secondary outcomes at T1 and
T2, whilst adjusting for baseline data. Ecological momentary assessment (EMA) will be piloted to assess functioning
in a subsample of participants.
Discussion: To the best of our knowledge, this will be the first RCT testing the effect of group MCT on multiple
insight dimensions (as primary outcome) in a sample of unselected patients with SSD, including several secondary
outcomes of clinical relevance, namely symptom severity, functioning, which will also be evaluated with EMA, hospitalizations and suicidal behaviour. | en_US |
dc.description.sponsorship | This study was supported by the Universidad Autónoma de Madrid and European Union via the Intertalentum Project Grant-Marie Skłodowska Curie Actions (GA 713366) to JDLM who is the Princiapl Investigator. This grant therefore funds both JDLM’s salary and the consumable expenses related to the study. JDLM, VGRR, ASEM, MLBE, LMI, LML, SSA, AAR and EBG’s salaries come from the Hospital Universitario Fundación Jiménez Díaz, where this study is currently being carried out, which therefore provides the necessary institutional/departmental support for its development. Additional departmental support concerning the use of Ecological Momentary Assessment (see Methods section, page 11 -last paragraph- and page 12 –first paragraph-, for details) is provided by the Instituto de Salud Carlos III (Madrid, Spain) (ISCIII PI16/01852) and the Madrid Regional Government (Madrid, Spain) (B2017/BMD-3740 AGES-CM 2CM; Y2018/TCS-4705 PRACTICO-CM). ASD acknowledges funding supports from University College London, which covers his salary | en_US |
dc.format.extent | 11 pag. | es_ES |
dc.format.mimetype | application/pdf | en |
dc.language.iso | eng | en_US |
dc.publisher | BMC part of Springer Nature | en_US |
dc.relation.ispartof | BMC Psychiatry | en_US |
dc.rights | © 2020 The Authors | en_US |
dc.subject.other | Schizophrenia spectrum disorders | en_US |
dc.subject.other | Metacognitive training | en_US |
dc.subject.other | Insight | en_US |
dc.subject.other | Ecological momentary assessment | en_US |
dc.title | Study protocol of a randomised clinical trial testing whether metacognitive training can improve insight and clinical outcomes in schizophrenia | en_US |
dc.type | article | en |
dc.subject.eciencia | Medicina | es_ES |
dc.relation.publisherversion | https://doi.org/10.1186/s12888-020-2431-x | es_ES |
dc.identifier.doi | 10.1186/s12888-020-2431-x | es_ES |
dc.identifier.publicationfirstpage | 30-1 | es_ES |
dc.identifier.publicationissue | 20 | es_ES |
dc.identifier.publicationlastpage | 30-11 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/H2020/713366/EU//MSCA | es_ES |
dc.relation.projectID | Gobierno de España. ISCIII PI16/01852 | es_ES |
dc.relation.projectID | Comunidad de Madrid. B2017/BMD-3740/AGES | es_ES |
dc.relation.projectID | Comunidad de Madrid. Y2018/TCS-4705/PRACTICO | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | en |
dc.rights.cc | Reconocimiento | es_ES |
dc.rights.accessRights | openAccess | en |
dc.authorUAM | Barrigón Estévez, María Luisa (278869) | |
dc.authorUAM | Baca García, Enrique (261227) | |
dc.authorUAM | López Moriñigo, Jorge David (319372) | |
dc.facultadUAM | Facultad de Medicina | |
dc.institutoUAM | Instituto de Investigación Sanitaria Fundación Jiménez Díaz (ISS-FJD) | |