dc.contributor.author | Amenós, Laura | |
dc.contributor.author | Trulli, Laura | |
dc.contributor.author | Nóvoa, Luis | |
dc.contributor.author | Parra, Alejandro | |
dc.contributor.author | Tortosa Manzanares, Mariola | |
dc.contributor.other | UAM. Departamento de Química Orgánica | es_ES |
dc.date.accessioned | 2021-03-02T19:20:06Z | |
dc.date.available | 2021-03-02T19:20:06Z | |
dc.date.issued | 2019-01-02 | |
dc.identifier.citation | Angewandte Chemie - International Edition 58.10 (2019): 3188-3192 | en_US |
dc.identifier.issn | 1433-7851 (print) | en_US |
dc.identifier.issn | 1521-3773 (online) | en_US |
dc.identifier.uri | http://hdl.handle.net/10486/693791 | |
dc.description | This is the peer reviewed version of the following article: Angewandte Chemie - International Edition 58.10 (2019): 3188-03192, which has been published in final form at https://doi.org/10.1002/anie.201812836. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions | en_US |
dc.description.abstract | We report a catalytic and stereospecific method for the preparation of enantioenriched α-hydroxy cyclopropylboronates with control in four contiguous stereocenters. The reaction involves the borylation of readily available allylic epoxides using an inexpensive Cu(I) salt and a commercially available phosphine ligand. High diastereocontrol is achieved and different diastereomers can be selectively prepared. Functionalization of the carbon–boron bond provides access to different enantiomerically enriched trisubstituted cyclopropanes from a common intermediate | en_US |
dc.description.sponsorship | We thank the European Research Council (ERC-337776) and MINECO (CTQ2016-78779-R) for financial support | en_US |
dc.format.extent | 7 pag. | es_ES |
dc.format.mimetype | application/pdf | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Wiley | es_ES |
dc.relation.ispartof | Angewandte Chemie - International Edition | en_US |
dc.rights | © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Herein | es_ES |
dc.subject.other | allylic epoxide | en_US |
dc.subject.other | boron | en_US |
dc.subject.other | copper | en_US |
dc.subject.other | cyclopropane | en_US |
dc.subject.other | cyclopropylboronate | en_US |
dc.title | Stereospecific synthesis of α-hydroxy-cyclopropylboronates from allylic epoxides | en_US |
dc.type | article | en_US |
dc.subject.eciencia | Química | es_ES |
dc.date.embargoend | 2021-01-02 | |
dc.relation.publisherversion | https://doi.org/10.1002/anie.201812836 | es_ES |
dc.identifier.doi | 10.1002/anie.201812836 | es_ES |
dc.identifier.publicationfirstpage | 3188 | es_ES |
dc.identifier.publicationissue | 10 | es_ES |
dc.identifier.publicationlastpage | 3192 | es_ES |
dc.identifier.publicationvolume | 58 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/FP7/337776 | es_ES |
dc.relation.projectID | Gobierno de España. CTQ2016-78779-R | es_ES |
dc.type.version | info:eu-repo/semantics/acceptedVersion | en |
dc.rights.accessRights | openAccess | es_ES |
dc.authorUAM | Parra Sánchez, Alejandro (263577) | |
dc.authorUAM | Tortosa Manzanares, Mariola (264632) | |
dc.facultadUAM | Facultad de Ciencias | |
dc.institutoUAM | Instituto de Investigación Avanzada en Ciencias Químicas (IAdChem) | |