Impact of recommended maternal vaccination programs on the clinical presentation of sars-cov-2 infection: A prospective observational study
Entity
UAM. Departamento de Obstetricia y GinecologíaPublisher
MDPI, Basel, SwitzerlandDate
2021-01-08Citation
10.3390/vaccines9010031
Vaccines 9.1 (2021): 31
ISSN
2076-393XDOI
10.3390/vaccines9010031Funded by
This research was supported by public funds obtained in competitive calls: Grant COV20/ 00021 from the Instituto de Salud Carlos III-Spanish Ministry of Health, and co-financed with Fondo Europeo de Desarrollo Regional (FEDER) fundsProject
Gobierno de España. COV20/00021Editor's Version
https://doi.org/10.3390/vaccines9010031Subjects
Covid 19; Diphtheria tetanus pertussis vaccine; Influenza vaccines; Maternal immunization; Passive immunization; Pregnancy; SARS-CoV-2; MedicinaRights
© 2021 The authorsAbstract
The COVID-19 pandemic has raised questions about the possible cross immunity resulting from common vaccination programs and SARS-CoV-2 infection. Therefore, the Spanish Obstetric Emergency group performed a multicenter prospective study on the vaccination status of Influenza and Tdap (diphtheria, tetanus and pertussis vaccine boost administered in adulthood) in consecutive cases of SARS-CoV-2 infection in a pregnancy cohort, in order to assess its possible association with the clinical presentation and severity of symptoms of SARS-CoV-2 infection, as well as to determine the factors that may affect vaccination adherence. A total of 1150 SARS-CoV-2 positive pregnant women from 78 Spanish hospitals were analyzed: 183 had not received either vaccine, 23 had been vaccinated for Influenza only, 529 for Tdap only and 415 received both vaccines. No association was observed between the vaccination status and the clinical presentation of SARS-CoV-2 infection and/or the severity of symptoms. However, a lower adherence to the administration of both vaccines was observed in the Latin-American subgroup. Based on the results above, we reinforce the importance of maternal vaccination programs in the actual pandemic. Health education campaigns should be specially targeted to groups less likely to participate in these programs, as well as for a future SARS-CoV-2 vaccination campaign.
Files in this item
Google Scholar:de la Cruz Conty, Maria Luisa
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Encinas Pardilla, Maria Begoña
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Garcia Sanchez, Marta
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Gonzalez Rodriguez, Laura
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Muner-Hernando, Marta Luisa
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Royuela Vicente, Ana
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Pintado Recarte, Pilar
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Martinez Varea, Alicia
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Martinez Diago, Clara
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Cruz Melguizo, Sara
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Martínez Pérez, Óscar
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