Daily sitting for long periods increases the odds for subclinical atheroma plaques
EntityUAM. Departamento de Medicina Preventiva y Salud Pública y Microbiología; Instituto de Investigación Sanitaria Hospital Universitario de La Paz (IdiPAZ)
PublisherMDPI, Basel, Switzerland
10.3390/jcm10061229Journal of Clinical Medicine 10.6 (2021): 1229
Funded byThis research was funded in part by CIBERCV and grants PI18/01929 and PI19/00948 from the Instituto de Salud Carlos III (co-supported by the European Regional Development Fund ‘Investing in your future’). J.L.P.-L. received a Grant FPU 2016 (FPU16/02539) from the Ministerio de Educación, Cultura y Deporte (Spain). M.L.’s research activity is funded by Agencia Aragonesa para la Investigación y el Desarrollo (ARAID)
ProjectGobierno de España. PI18/01929; Gobierno de España. PI19/00948
SubjectsCardiovascular disease; Sedentary behavior; Sitting time; Subclinical atherosclerosis; Medicina
Rights© 2021 The authors
Esta obra está bajo una Licencia Creative Commons Atribución 4.0 Internacional.
Sedentarism is a risk factor for cardiovascular disease (CVD), but currently it is not clear how a sedentary behavior such as long sitting time can affect atherosclerosis development. This study examined the relationship between sitting time and the prevalence of carotid and femoral subclinical atherosclerosis. A cross-sectional analysis based on a subsample of 2082 participants belonging to the Aragon Workers’ Health Study was carried out. Ultrasonography was used to assess the presence of plaques in carotid and femoral territories; the validated Spanish version of the questionnaire on the frequency of engaging in physical activity used in the Nurses’ Health Study and the Health Professionals’ was used to assess physical activity and sitting time; and demographic, anthropometric, and clinical data were obtained by trained personnel during the annual medical examination. Participants were categorized into <9 h/day and ≥9 h/day sitting time groups. After adjusting for several confounders, compared with participants that remain seated <9 h/day, those participants who remain seated ≥9 h/day had, respectively, OR = 1.25 (95%CI: 1.01, 1.55, p < 0.05) and OR = 1.38 (95%CI: 1.09, 1.74, p < 0.05) for carotid and any-territory plaque presence. Remaining seated ≥9 h/day is associated with higher odds for carotid and any-territory plaque presence independently of physical activity levels and other cardiovascular risk factors.
Google Scholar:Perez-Lasierra, Jose Luis - Laclaustra, Martin - Guallar Castillón, María Pilar - Casasnovas, Jose Antonio - Casajús, Jose Antonio - Jarauta, Estibaliz - Gonzalez-Agüero, Alejandro - Moreno-Franco, Belen
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Donat-Vargas, Carolina; Sandoval-Insausti, Helena; Peñalvo, José L.; Moreno Iribas, Maria Concepción; Amiano, Pilar; Bes-Rastrollo, Maira; Molina-Montes, Esther; Moreno-Franco, Belén; Agudo, Antonio; Mayo, Cristina Lasheras; Laclaustra, Martín; De La Fuente Arrillaga, Carmen; Chirlaque Lopez, Maria Dolores; Sánchez, Maria José; Martínez-Gonzalez, Miguel Angel; Pilar, Guallar Castillón