Disposable screen-printed carbon-based electrodes in amperometric detection for simultaneous determination of parabens in complex-matrix personal care products by HPLC
Entity
UAM. Departamento de Química Analítica y Análisis InstrumentalPublisher
ElsevierDate
2022-04-06Citation
10.1016/j.talanta.2022.123459
Talanta 245 (2022): 123459
ISSN
0039-9140 (print); 1873-3573 (online)DOI
10.1016/j.talanta.2022.123459Funded by
Lucia Abad acknowledges to Universidad Autonoma de Madrid for the predoctoral fellowship (FPI-UAM program). Sergio Lucas and Carmen Isabel thanks to Community of Madrid and European Social Fund for the contracts PEJ-2018-AI/BIO-11845 and PEJ-2019-TL/IND-14286, respectively through the Youth Employment Initiative (YEI)Editor's Version
https://doi.org/10.1016/j.talanta.2022.123459Subjects
Carbon-based SPE; Electrochemical detection; High performance liquid chromatography; Paraben; Personal care products; Ultrasound assisted extraction; QuímicaRights
© 2022 The AuthorsEsta obra está bajo una licencia de Creative Commons Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional.
Abstract
Parabens are chemicals widely used as preservatives in different types of industrial products. In recent years, the
concern about the safety of these compounds has increased due to their endocrine disrupting activity. For this
reason, their use is highly regulated and even some of them have already been banned. Thus, methods for the
sensitive and selective detection of these compounds are required to control their presence in food, cosmetic, and
pharmaceutical products. This paper presents an HPLC method with electrochemical detection using disposable
screen-printed electrodes (SPE) for simultaneous determination of 6 different parabens in personal care products.
Electrochemical behaviour of parabens was studied on SPE with different carbon-based materials as working
electrode: carbon, ordered mesoporous carbon and graphene. From these studies, pH, detection potential, and
the most adequate SPE were chosen. Due to the wide range of textures and viscosities (e.g., liquid, solid, and
semi-solid) of personal care products, adequate sample pretreatments are required before chromatographic
measurement. Here, a fast ultrasound-assisted extraction method was applied to simultaneously extract 6 parabens (methyl-, ethyl-, isopropyl-, propyl-, butyl-and benzyl-paraben) from different complex-matrix cosmetic
products. Instrumental limits of detection between 20 and 115 μg L− 1 were obtained applying +1.0 V (vs. Ag) as
detection potential on carbon-based SPE. The total analysis time, including sample extraction and HPLC run, was
shorter than 35 min. The proposed method is more versatile and faster than the current available methods and
has been successfully applied to determine parabens in commercial samples such as shampoos, body creams,
facial tonics, and toothpastes
Files in this item
Google Scholar:Lucas Sánchez, Sergio
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Abad Gil, Lucía
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Isabel Cabrera, Carmen
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Gismera García, María Jesús
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Sevilla Escribano, M. Teresa
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Procopio, Jesús R.
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