Chronodisruption and ambulatory circadian monitoring in cancer patients: beyond the body clock
10.1007/s11912-021-01158-zCurrent Oncology Reports 24.2 (2022):135–149
ISSN1523-3790 (print); 1534-6269 (online)
Funded byThis work was supported in part by CLARIFY project, within European Union’s Horizon 2020 Research and Innovation Programme under grant agreement No. 875160, Instituto de Fomento de la Región de Murcia (INFO) and the European Regional Development Fund (FEDER)
SubjectsAmbulatory circadian monitoring; Cancer patients; Chronodisruption; Circadian rhythms; Multi-modal sensors; Tumorigenesis; Medicina
Rights© The Author(s) 2022
Esta obra está bajo una Licencia Creative Commons Atribución 4.0 Internacional.
Circadian rhythms impose daily rhythms a remarkable variety of metabolic and physiological functions, such as cell proliferation, inflammation, and DNA damage response. Accumulating epidemiological and genetic evidence indicates that circadian rhythms’ disruption may be linked to cancer. The integration of circadian biology into cancer research may offer new options for increasing cancer treatment effectiveness and would encompass the prevention, diagnosis, and treatment of this disease. Recent Findings: In recent years, there has been a significant development and use of multi-modal sensors to monitor physical activity, sleep, and circadian rhythms, allowing, for the very first time, scaling accurate sleep monitoring to epidemiological research linking sleep patterns to disease, and wellness applications providing new potential applications. Summary: This review highlights the role of circadian clock in tumorigenesis, cancer hallmarks and introduces the state-of-the-art in sleep-monitoring technologies, discussing the eventual application of insights in clinical settings and cancer research
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Google Scholar:Almaida-Pagan, Pedro F. - Torrente, María - Campos Yuste, Manuel - Provencio Pulla, Mariano - Madrid, Juan Antonio - Franco Pérez, Fernando Fabio - Morilla, Beatriz Rodríguez - Cantos, Blanca - Sousa, Pedro A. - Martínez Madrid, María José - Pimentao, Joao - Rol, María Ángeles
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