Antibacterial activity and kinetic release of Laureliopsis philippiana (looser) essential oil from nanostructured porous silicon with surface-functionalization alternatives
EntityUAM. Departamento de Física Aplicada
10.3390/app12168258Applied Sciences 12.16 (2022): 8258
SubjectsEssential Oils; Thymus Plant; Antimicrobial Activity; Física
Rights© 2022 by the authors
Esta obra está bajo una Licencia Creative Commons Atribución 4.0 Internacional.
In this work, the antibacterial activity of Laureliopsis philippiana (Looser) essential oil was studied, and its kinetic release performance using different surface-functionalized nanostructured porous silicon (nPSi) was analyzed. Experimental results showed the high inhibitory effect of Laureliopsis philippiana essential oil against Staphylococcus aureus and Klebsiella pneumoniae. In addition, the essential oil was successfully loaded into different kinds of functionalized nPSi. FTIR measurements indicated the formation of stable complexes in the nPSi functionalization process. Specifically, chemical oxidized nPSi (nPSi-Ox), 3-aminopropyltriethoxysilane functionalized nPSi (nPSi-APTS), undecylenic acid-functionalized nPSi (nPSi-UAc), chitosan (nPSi-Chi) and β-cyclodextrin (nPSi-βCD) polymer functionalization on nPSi were studied. nPSi-Ox, nPSi-APTS, and nPSi-UAc were covalent functionalization, and nPSi-Chi and nPSi-βCD were obtained by electrostatic attachment. The kinetic study demonstrated a controlled release of up to 4 h for all the samples following a quasi-Fickian diffusion mechanism. Moreover, the use of functionalized nPSi-APTS and nPSi-UAc structures allows a more controlled kinetic release of Laureliopsis philippiana essential oil in comparison to the rest of the functionalization, increasing its availability and exposure to the environment
Google Scholar:Pérez-San Martín, Andrés - Uribe, Karina - Hernández-Montelongo, Jacobo - Naveas, Nelson - Manso Silván, Miguel - Oyarzún, Patricio - Díaz-García, Víctor - Contreras, Braulio - Recio-Sánchez, Gonzalo
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