DUbbing language-therapy CINEma-based in aphasia post-stroke (DULCINEA): study protocol for a randomized crossover pilot trial
AuthorFuentes Gimeno, Blanca Eulalia; Fuente-Gómez, Lydia de la; Sempere-Iborra, Cristian; Delgado-Fernández, Celia; Tarifa-Rodríguez, Aida; Alonso de Leciñana Cases, María; De Celis-Ruiz, Elena; Gutiérrez-Zúñiga, Raquel; López-Tàppero, José; Martín Alonso, Marta; Pastor Yborra, Sylvia; Rigual, Ricardo; Ruiz-Ares, Gerardo; Rodríguez-Pardo, Jorge; Virues-Ortega, Javier; Borobia Pérez, Alberto M.; Blanco, Paloma; Bueno-Guerra, Nereida
EntityUAM. Departamento de Medicina
10.1186/s13063-021-05956-5Trials 23 (2022): 21
Funded byThis study is promoted by Blanca Fuentes and the Research Foundation of La Paz University Hospital, which hosts a research consortium joined by the Department of Neurology at La Paz University Hospital, the Department of Psychology at Comillas Pontifical University, and the patients’ association Afasia Activa. This project has received funding from “la Caixa” Banking Foundation under the project code HR18-00026. Funder is not involved in any of the following processes: design of the trial, data collection, analysis, or interpretation of data nor than in writing the manuscript
SubjectsAphasia; Protocol; Randomized clinical trial; Stroke; Medicina; Psicología
Rights© The Author(s). 2022
Esta obra está bajo una Licencia Creative Commons Atribución 4.0 Internacional.
Communication is one of the most important predictors of social reintegration after stroke. Approximately 15–42% of stroke survivors experience post-stroke aphasia. Helping people recover from aphasia is one of the research priorities after a stroke. Our aim is to develop and validate a new therapy integrating dubbing techniques to improve functional communication. Methods: The research project is structured as three work packages (WP). WP1: development of the dubbed language cinema-based therapy: Two research assistants (a speech therapist and a dubbing actor) will select the clips, mute specific words/sentences in progressive speech difficulty, and guide patients to dub them across sessions. Words to be dubbed will be those considered to be functionally meaningful by a representative sample of aphasic patients and relatives through an online survey. WP2: a randomized, crossover, interventional pilot study with the inclusion of 54 patients with post-stroke non-fluent aphasia. Patients will be treated individually in 40-min sessions twice per week for 8 weeks. Primary outcomes will be significant pre/post differences in scores in the Communicative Activity Log (CAL) questionnaire and Boston Diagnostic Aphasia Examination (BDAE) administered by a psychologist blinded to the patients’ clinical characteristics. Secondary outcomes: General Health Questionnaire (GHQ)-12, Stroke Aphasia Quality of Life Scale (SAQOL-39), Western Aphasia Battery Revised (WAB-R), and the Stroke Aphasic Depression Questionnaire (SADQ10). WP3: educational activities and dissemination of results. WP3 includes educational activities to improve public knowledge of aphasia and dissemination of the results, with the participation of the Spanish patients’ association Afasia Activa. Discussion: This pilot clinical trial will explore the efficacy of a new therapeutic tool based on dubbing techniques and computer technology to improve functional communication of patients suffering from post-stroke aphasia with the use of standardized test assessment
Google Scholar:Fuentes Gimeno, Blanca Eulalia - Fuente-Gómez, Lydia de la - Sempere-Iborra, Cristian - Delgado-Fernández, Celia - Tarifa-Rodríguez, Aida - Alonso de Leciñana Cases, María - De Celis-Ruiz, Elena - Gutiérrez-Zúñiga, Raquel - López-Tàppero, José - Martín Alonso, Marta - Pastor Yborra, Sylvia - Rigual, Ricardo - Ruiz-Ares, Gerardo - Rodríguez-Pardo, Jorge - Virues-Ortega, Javier - Borobia Pérez, Alberto M. - Blanco, Paloma - Bueno-Guerra, Nereida
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