Protein biomarkers for the diagnosis of alzheimer’s disease at different stages of neurodegeneration
Entity
UAM. Departamento de Biología MolecularPublisher
MDPIDate
2020-09-02Citation
10.3390/ijms21186749
International Journal of Molecular Sciences 21.18 (2020): 6749
ISSN
1661-6596 (print); 1422-0067 (online)DOI
10.3390/ijms21186749Editor's Version
https://doi.org/10.3390/ijms21186749Subjects
Protein; Tau Protein; Biological Marker; Protein Phosphorylation; Alzheimer Disease; Cerebrospinal Fluid; Biología y Biomedicina / Biología; MedicinaRights
© 2020 The Author(s)Abstract
Mainly obtained from familial Alzheimer’s disease patients’ data, we know that some features of the neurodegenerative start several years before the appearance of clinical symptoms. In this brief review, we comment on some molecular and cellular markers appearing at different stages of the disease, before or once the clinical symptoms are evident. These markers are present in biological fluids or could be identified by image techniques. The combined use of molecular and cellular markers will be of interest to determine the development of the different phases of the disease
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Google Scholar:Pérez Martínez, María Mar
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Hernández Pérez, Félix
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Ávila, Jesús
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