The influence of puberty on vitamin D status in obese children and the possible relation between vitamin D deficiency and insulin resistance

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dc.contributor.author Gutiérrez Medina, Sonsoles
dc.contributor.author Gavela Pérez, Teresa
dc.contributor.author Domínguez-Garrido, María Nieves
dc.contributor.author Gutiérrez-Moreno, Elisa
dc.contributor.author Rovira, Adela
dc.contributor.author Garcés, Carmen
dc.contributor.author Soriano-Guillén, Leandro
dc.contributor.other UAM. Departamento de Pediatría es_ES
dc.contributor.other Instituto de Investigación Sanitaria Fundación Jiménez Díaz (ISS-FJD) es_ES
dc.date.accessioned 2016-07-21T17:15:08Z
dc.date.available 2016-07-21T17:15:08Z
dc.date.issued 2015-01-01
dc.identifier.citation Journal of Pediatric Endocrinology and Metabolism 28.(1.2) 2015: 105-110 en_US
dc.identifier.issn 0334-018X (print) es_ES
dc.identifier.issn 2191-0251 (on line) es_ES
dc.identifier.uri http://hdl.handle.net/10486/672199
dc.description.abstract Background: Puberty can affect vitamin D levels. Objectives: The goal of this study was to analyze the relation between vitamin D deficiency and puberty in obese Spanish children, along with the possible interrelation between vitamin D status and degree of insulin resistance. Methods: A cross-sectional study was carried out, in which clinical and biochemical data were gathered from 120 obese and 50 normal weight children between January 2011 and January 2013. Results: Mean vitamin D levels were 19.5 and 31.6 ng/mL in obese pubertal and obese prepubertal children, respectively. About 75% of the obese pubertal subjects and 46% of the obese prepubertal subjects had vitamin D deficiency. Vitamin D levels were significantly lower in pubescent subjects compared with pre-pubescent subjects in summer, fall, and winter. There was no apparent relation between vitamin D levels and homeostasis model assessment index for insulin resistence (expressed in standard deviation score for sex and Tanner stage) in either puberty or pre-puberty. Conclusion: Puberty may be a risk factor for the vitamin D deficiency commonly found in the obese child population. This deficiency is not associated with higher insulin resistance in obese pubertal children compared with obese prepubertal children en_US
dc.format.extent 6 pag. es_ES
dc.format.mimetype application/pdf en
dc.language.iso eng en
dc.publisher De Gruyter en_US
dc.relation.ispartof Journal of Pediatric Endocrinology and Metabolism en_US
dc.subject.other Childhood obesity en_US
dc.subject.other Insulin resistance en_US
dc.subject.other Puberty en_US
dc.subject.other Vitamin D en_US
dc.title The influence of puberty on vitamin D status in obese children and the possible relation between vitamin D deficiency and insulin resistance en_US
dc.type article en
dc.subject.eciencia Medicina es_ES
dc.relation.publisherversion http://dx.doi.org/10.1515/jpem-2014-0033 es_ES
dc.identifier.doi 10.1515/jpem-2014-0033 es_ES
dc.identifier.publicationfirstpage 105 es_ES
dc.identifier.publicationissue 1-2 es_ES
dc.identifier.publicationlastpage 110 es_ES
dc.identifier.publicationvolume 28 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion en
dc.rights.accessRights openAccess en
dc.authorUAM Gavela Pérez, Teresa (262643)


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