Generation of a human iPSC line from a patient with Leigh syndrome caused by a mutation in the MT-ATP6 gene
Entity
UAM. Departamento de Bioquímica; Instituto de Investigaciones Biomédicas "Alberto Sols" (IIBM)Publisher
Elsevier B.V.Date
2016-05-01Citation
10.1016/j.scr.2016.04.012
Stem Cell Research 16 (2016): 766-769
ISSN
1873-5061DOI
10.1016/j.scr.2016.04.012Funded by
This work was supported by grants from the “Centro de Investigación Biomédica en Red en enfermedades raras” (CIBERER) (Grant 13-717/132.05 to RG), the “Instituto de Salud Carlos III” (FIS PI10/0703 and PI13/00556 to RG and PI15/00484 to MEG cofunded by FEDER), “Comunidad Autónoma de Madrid” (grant number S2010/BMD-2402 to R.G); T.G-M. receives grant support from the Universidad Autónoma de Madrid, FPI-UAM and F.Z-D. from the Ministerio de Educación, Cultura y Deporte, grant number FPU13/00544. M.E.G. is senior staff scientist at the “Centro de Investigación Biomédica en Red en Enfermedades Raras” (CIBERER)Project
Comunidad de Madrid. S2010/ BMD-2402/MITOLAB; Gobierno de España. FPU13/00544Editor's Version
http://dx.doi.org/10.1016/j.scr.2016.04.012Subjects
Human iPSC line; Leigh syndrome; Mutation; MT-ATP6 gene; MedicinaRights
© 2016 The AuthorsEsta obra está bajo una licencia de Creative Commons Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional.
Abstract
Human iPSC line L749.1 was generated from fibroblasts of a patient with Leigh syndrome associated with a heteroplasmic mutation in the MT-ATP6 gene. Reprogramming factors OCT4, SOX2, CMYC and KLF4 were delivered using retroviruses.
Files in this item
Google Scholar:Galera-Monge, Teresa
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Zurita-Díaz, Francisco
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González-Páramos, Cristina
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Moreno-Izquierdo
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Fraga, Mario F.
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Fernández, Agustín F.
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Garesse Alarcón, Rafael
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Gallardo, M.Esther
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